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Updated: Mar 19, 2026

The Multiple Sclerosis Performance Test MSPT: An iPad-Based Disability Assessment Tool
Published on: June 30, 2014
Positive correlation between functional disability, excessive daytime sleepiness, and fatigue in relapsing-remitting
Douglas Martins Braga1, Gilmar Fernandes do Prado1, Denis Bernardi Bichueti1
1Universidade Federal de São Paulo, Universidade Federal de São Paulo, Departamento de Neurologia e Neurocirurgia, São Paulo SP , Brasil, Universidade Federal de São Paulo, Departamento de Neurologia e Neurocirurgia, Setor de Doenças Desmielizantes e Neuro-sono, São Paulo SP, Brasil.
Method:
Retrospective review of medical records from patients with multiple sclerosis to collect data on severity of fatigue, disability, daytime sleepiness, and depression. From 912 medical records reviewed, 122 reported daytime sleepiness: 67% had relapsing remitting, 12% had primary progressive, and 21% had secondary progressive.
Results:
In 95% of the patients with relapsing remitting who complained of daytime sleepiness and fatigue, association was found between these symptoms and neurological disability. Patients with relapsing remitting who complained of daytime sleepiness and fatigue also experienced depression (p = 0.001). No association between fatigue, excessive daytime sleepiness, depression, and disability was found in patients with progressive disease.
Conclusion:
In relapsing remitting, there is correlation between functional disability, excessive daytime sleepiness and fatigue, a finding not confirmed in primary progressive and secondary progressive form.
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