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Purification of H3 and H4 Histone Proteins and the Quantification of Acetylated Histone Marks in Cells and Brain Tissue
Published on: November 30, 2018
InterFeriNg with Acetγlation: Stress-Levels of Acetate Improve Memory T Cell Function
Caroline A Lewis1, Matthew G Vander Heiden1
1The Koch Institute for Integrative Cancer Research, MIT, Cambridge, MA 02139, USA.
Abstract:
Catabolic stress can lead to changes in circulating acetate levels. In this issue of Immunity, Balmer et al. (2016) report that serum acetate increases in response to acute infection and describe a mechanism by which this results in acetylation of the glycolytic enzyme GAPDH and improves the recall function of memory CD8(+) T cells.
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