The Clot Strikes Thrice: Case Report of a Patient with 3 Concurrent Embolic events

Chee-Keong Wee1, Tushar Divakar Gosavi11, Weiting Huang2

  • 1National Neuroscience Institute, Singapore General Hospital Campus, Singapore.

Insights

Concurrent cerebral and systemic embolism are rare. A large left ventricular thrombus caused multiple emboli, but urgent anticoagulation after stroke led to a good outcome.

Area of Science:

  • Cardiology
  • Neurology

Background:

  • Concurrent cerebral and systemic embolism are uncommon, with acute myocardial infarction from coronary embolism being particularly rare.
  • Left ventricular thrombus is a known cause of systemic embolism.

Observation:

  • A 49-year-old man presented with cerebral infarction due to right posterior cerebral artery occlusion.
  • He subsequently developed chest pain and ST-elevation myocardial infarction, diagnosed as right coronary artery occlusion.
  • Further investigation revealed a right profunda femoris artery occlusion, indicating three concurrent embolic events.

Findings:

  • Echocardiography identified a large, mobile left ventricular thrombus as the source of the emboli.
  • Urgent anticoagulation therapy was initiated.
  • The patient recovered and was discharged after one month of rehabilitation with no further ischemic events.

Implications:

  • This case highlights the potential for a single left ventricular thrombus to cause widespread embolic events.
  • In select patients with high embolic risk, initiating urgent anticoagulation following acute ischemic stroke may be a viable treatment strategy.
  • Early diagnosis and management of left ventricular thrombus are crucial to prevent severe embolic complications.
Abstract

Related Concept Videos

Pulmonary Embolism III: Nursing Management01:27

Pulmonary Embolism III: Nursing Management

A pulmonary embolism occurs when a thrombus, amniotic fluid, tumor tissue, fat, or air embolus blocks one or more pulmonary arteries. Effective nursing management and patient education are crucial for improving outcomes and preventing recurrence.Nursing management starts with obtaining a comprehensive patient history, particularly noting any history of deep vein thrombosis (DVT). Assess for clinical manifestations, including dyspnea, chest pain, crackles, heart murmurs, and signs of right-sided...
618
Pulmonary Embolism II: Diagnostic Studies and Interprofessional Care01:29

Pulmonary Embolism II: Diagnostic Studies and Interprofessional Care

Diagnosing Pulmonary EmbolismDiagnosing pulmonary embolism (PE) involves clinical assessment and advanced imaging tests. The preferred diagnostic tool is the spiral (helical) CT scan or CT angiography (CTA), which uses intravenous contrast media to visualize the pulmonary vasculature and identify emboli.A ventilation-perfusion (V/Q) scan is an alternative for patients unable to receive contrast media. This scan includes both perfusion and ventilation scanning. Perfusion scanning involves...
629
Pulmonary Embolism I: Introduction01:29

Pulmonary Embolism I: Introduction

Pulmonary embolism (PE) occurs when a thrombus, fat or air embolus, amniotic fluid, or tumor tissue blocks one or more pulmonary arteries. These blockages originate in the venous system or the right side of the heart.EtiologyPE primarily arises from deep vein thrombosis (DVT) and other hypercoagulable states, such as inherited thrombophilias. Additional etiological factors include venous stasis, commonly seen in obesity, and endothelial injury from surgery and trauma. Less common causes include...
1.1K
Venous Thrombosis IV: Nursing Management01:30

Venous Thrombosis IV: Nursing Management

Nursing management begins with a thorough assessment of the patient's health history. Key factors include trauma to veins, peripherally inserted central catheters, varicose veins, recent pregnancy or childbirth, surgery, bacteremia, prolonged bed rest, atrial fibrillation, COPD, heart failure, cancer, coagulation disorders, myocardial infarction, spinal cord injury, stroke, prolonged travel, recent bone fractures, and dehydration. Review medication intake, particularly oral contraceptives,...
360
Venous Thrombosis III: Interprofessional Care01:29

Venous Thrombosis III: Interprofessional Care

Venous thrombosis requires effective prevention and treatment strategies to improve patient outcomes and reduce potential complications.Prevention StrategiesHealthcare providers must prioritize preventing venous thromboembolism (VTE) for all adult patients upon admission. Interventions depend on bleeding and thrombosis risk, medical history, current medications, diagnoses, planned procedures, and patient preferences. Patients on bed rest should change positions every two hours and, if not...
455
Aneurysm II: Clinical Manifestations and Diagnostic Studies01:21

Aneurysm II: Clinical Manifestations and Diagnostic Studies

Thoracic, aortic arch and abdominal aneurysms are significant vascular conditions that can present with various clinical manifestations and lead to serious complications. Understanding these manifestations and the appropriate diagnostic studies is essential for effective management and treatment.Thoracic Aortic AneurysmsThoracic aortic aneurysms often remain asymptomatic until they reach a size that impinges on adjacent structures. They typically cause deep, diffuse chest pain that radiates to...
486