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Related Concept Videos

Sample Preparation for Analysis: Overview01:21

Sample Preparation for Analysis: Overview

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Sample preparation is an essential step in the analytical process. It involves preparing a sample so that it can be analyzed accurately. The goal is to extract the analyte, the substance you want to measure, from the sample while removing any components that may interfere with the analysis. Sample preparation techniques vary depending on the physical state of the sample.
Bulk or large solid samples are typically reduced in size using grinding, crushing, or milling techniques to increase the...
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Sample Preparation for Analysis: Advanced Techniques01:08

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Accurate analysis of complex samples often requires advanced preparation techniques to achieve reliable and reproducible results. Samples containing inorganic or organic materials can be challenging to dissolve or decompose effectively. Standard sample preparation methods include acid digestion, fusion, dry ashing, and wet digestion.
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Preparation of Samples for Electron Microscopy01:20

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To be visualized by an electron microscope, either transmission or scanning, biological samples need to be fixed (stabilized) so the electron beam does not destroy them and dried thoroughly (desiccated/dehydrated) so the vacuum does not affect them. Fixation needs to be done as quickly as possible because the sample properties will start changing as soon as it is removed from its natural environment. For example, in a tissue sample, the oxygen levels begin decreasing, causing an altered...
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Sample Handling01:02

Sample Handling

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Transportation of samples from the collection point to the laboratory, as well as storage and preservation techniques, are crucial for maintaining sample integrity and ensuring accurate and reliable test results.
Samples should be transported carefully from collection points to the laboratory. They should be properly sealed and clearly labeled to prevent cross-contamination. To preserve the sample integrity, optimal temperature conditions during transport are essential. This could involve using...
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Related Experiment Video

Updated: Mar 19, 2026

Author Spotlight: Technologies and Challenges in Elemental Analysis of Food Samples
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Current trends in sample preparation for cosmetic analysis.

Zhixiong Zhong1, Gongke Li2

  • 1Center for Disease Control and Prevention of Guangdong Province, Guangzhou, China.

Journal of Separation Science
|June 24, 2016
PubMed
Summary
This summary is machine-generated.

This review covers recent advancements in cosmetic sample preparation techniques (2010-2016). It highlights methods for analyzing restricted ingredients and prohibited substances to ensure cosmetic safety.

Keywords:
Active ingredientsCosmeticsProhibited substancesSample preparation

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Area of Science:

  • Analytical Chemistry
  • Cosmetic Science

Background:

  • Cosmetics are widely used, necessitating rigorous safety analysis.
  • Identifying restricted and prohibited substances is crucial for cosmetic safety.
  • Complex cosmetic matrices pose challenges for accurate analysis.

Purpose of the Study:

  • To review new sample preparation techniques for cosmetic analysis developed between 2010 and 2016.
  • To discuss the application of these techniques in separating and purifying cosmetic ingredients and contaminants.

Main Methods:

  • Liquid-phase microextraction
  • Solid-phase microextraction
  • Matrix solid-phase dispersion
  • Pressurized liquid extraction
  • Cloud point extraction
  • Ultrasound-assisted extraction
  • Microwave digestion

Main Results:

  • Several novel sample preparation techniques have emerged for cosmetic analysis.
  • These methods improve the efficiency of separating and determining target analytes in complex cosmetic samples.
  • Progress has been made in applying these techniques for both allowed ingredients and prohibited substances.

Conclusions:

  • Advanced sample preparation is vital for ensuring cosmetic product safety.
  • The reviewed techniques offer improved analytical capabilities for cosmetic quality control.
  • Continued research in sample preparation will enhance the detection of cosmetic contaminants and ensure regulatory compliance.