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Updated: Mar 19, 2026

3D-Neuronavigation In Vivo Through a Patient's Brain During a Spontaneous Migraine Headache

3D-Neuronavigation In Vivo Through a Patient's Brain During a Spontaneous Migraine Headache

Published on: June 2, 2014

The migraine postdrome: An electronic diary study.

Nicola J Giffin¹, Richard B Lipton¹, Stephen D Silberstein¹

¹From the Department of Neurology (N.J.G.), Royal United Hospital, Bath, UK; Albert Einstein College of Medicine (R.B.L.), New York, NY; Thomas Jefferson University (S.D.S.), Philadelphia, PA; Danish Headache Centre (J.O.), Glostrup Hospital, Denmark; NIHR-Wellcome Trust King's Clinical Research Facility (P.J.G.), King's College London, UK; and Department of Neurology (P.J.G.), University of California, San Francisco.

|June 24, 2016

Summary

This summary is machine-generated.

Migraine postdrome symptoms are common, with 81% of patients experiencing fatigue and concentration issues after headache resolution. These non-headache symptoms significantly impact daily functioning and distress.

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Area of Science:

Neurology
Clinical Neuroscience

Background:

Migraine is a debilitating neurological disorder.
The postdrome phase of migraine, following headache resolution, is often overlooked.
Understanding postdrome symptoms is crucial for comprehensive migraine management.

Purpose of the Study:

To investigate the prevalence and nature of non-headache symptoms during the migraine postdrome.
To assess the impact of postdrome symptoms on patients' overall functioning.

Main Methods:

A 3-month prospective electronic diary study involving 120 migraine patients.
Daily collection of non-headache symptoms experienced before, during, and after headache.
Utilized visual analogue scales to measure functioning and headache severity.

Main Results:

81% of patients reported at least one non-headache symptom in the postdrome.
Common postdrome symptoms included fatigue, difficulty concentrating, and neck stiffness.
Overall health scores remained low during the postdrome, indicating persistent disability.

Conclusions:

Non-headache symptoms are prevalent in the migraine postdrome and contribute to patient distress and disability.
Further research, including larger observational studies and clinical trials, is warranted.
Systematic recording of postdrome symptoms is essential for evaluating migraine treatments.