Related Experiment Video
Updated: Mar 19, 2026

Quantification of Macronutrients Intake in a Thermogenetic Neuronal Screen using Drosophila Larvae
Published on: June 11, 2020
[Association between the feeding behavior factors and the expression of DRD2 gene: a study of mexican monozygotic
Alma Genis-Mendoza1,2, Humberto Nicolini2, Carlos Alfonso Tovilla-Zárate3
1Hospital Infantil Juan N. Navarro, Secretaría de Salud, Ciudad de México, México.
Introduction:
The feeding behavior in humans is complex, with psychological, social, and cultural factors. This pathology consists of the desire to eat (reinforcement/reward) and the control of the act of eating (inhibitory control). It is well known that blocking post-synaptic D2 receptors in the nucleus accumbens induces a decrease of craving behavior. Due to this, to test hypothesis we measured the expression of the DRD2 gene and the expression of the type of feeding factor in a group of Mexican twins.
Methods:
In the study were included 18 pairs of twins (n = 36), reared together (at least up to 18 years old); native to Mexico City; to whom we applied the three factors of food instrument.
Results:
We observed a significant correlation between the "uncontrolled" factor and expression of the DRD2 gene (p < 0.03).
Conclusion:
Therefore, we propose that the expression of the DRD2 gene in subjects is a linkage to the type of feeding factor.
More Related Videos
07:54Applying Stereotactic Injection Technique to Study Genetic Effects on Animal Behaviors
Published on: May 10, 2015
09:23Quantification of Information Encoded by Gene Expression Levels During Lifespan Modulation Under Broad-range Dietary Restriction in C. elegans
Published on: August 16, 2017
Related Concept Videos
Behavioral Genetics and Its Designs
The primary methodologies used in behavior genetics include family studies, twin studies, and adoption studies, each providing unique...
Human Genetics
The complex relationship between genetics and psychology is observable through common biological components such...
Lethal Alleles
Lucien Cuénot discovered lethal alleles in 1905 while studying the inheritance of coat color in mice. The agouti gene is responsible for the color of the coat in mice. This gene codes for an agouti-signaling protein, which is responsible for melanin distribution in mammals. The wild-type allele gives rise to gray-brown coat color in mice, while the mutant allele gives rise to yellow coat color. In addition to coat color, the agouti gene is associated with the yellow...
Incomplete Dominance
Epistasis Analysis
Background and Environment Affect Phenotype
An example of how genetic background affects phenotype can be seen in horses. The Extension gene in horses is responsible for their coat color. A wild-type gene (EE) produces black pigment in the coat, while a mutant gene (ee) produces red pigment. A...