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Reduced central line infection rates in children with leukemia following caregiver training: A quality improvement
Andrea Lo Vecchio1, Joshua K Schaffzin, Eliana Ruberto
1Department of Translational Medical Science, Section of Pediatrics, University of Naples Federico II, Naples, Italy Division of Infectious Diseases, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio Onco-Hematology Unit, Santobono-Pausilipon Children's Hospital Department of Pediatrics, Azienda Ospedaliera Universitaria Federico II, Naples, Italy.
Insights
Caregiver education on central-line (CL) management significantly reduced central-line-associated bloodstream infections (CLABSI) in children with acute leukemia. This quality improvement initiative demonstrated the effectiveness of training high-risk pediatric patients’ caregivers.
Area of Science:
- Pediatric Oncology
- Infectious Diseases
- Quality Improvement Science
Background:
- Infections pose a significant threat to children with acute leukemia, with central-line devices increasing their risk of serious infections.
- Central-line-associated bloodstream infections (CLABSI) are a major concern in immunocompromised pediatric populations.
Purpose of the Study:
- To evaluate the impact of caregiver education on central-line management on the CLABSI rate in children with acute leukemia.
- To assess the effectiveness of a quality improvement intervention focused on caregiver training.
Main Methods:
- A quality improvement project involving 9 in-person education and practice sessions for caregivers of children with acute leukemia.
- Training utilized mannequins and direct patient scenarios to enhance CL management skills.
- Data on CLABSI rates were collected before and after the caregiver education intervention.
Main Results:
- The overall CLABSI rate decreased by 46% (from 6.86 to 3.70 per 1000 central-line days) post-intervention.
- Children whose caregivers completed training had significantly lower CLABSI rates (1.74/1000 CL-days) compared to those without training (12.2/1000 CL-days).
- Caregivers in training also showed a lower CLABSI rate (3.96/1000 CL-days) than those not trained.
Conclusions:
- Caregiver education in central-line management, as part of a quality improvement initiative, effectively reduced CLABSI rates in pediatric acute leukemia patients.
- The active involvement and specific training of caregivers are crucial for minimizing CLABSI risk in high-risk children.
- This approach highlights the potential of empowering caregivers to improve patient safety and outcomes.
Abstract:
Infections are a leading cause of morbidity and mortality in children with acute leukemia. Central-line (CL) devices increase this population's risk of serious infections.Within the context of a quality improvement (QI) project, we tested the effect of caregiver education on CL management on the CL-associated bloodstream infection (CLABSI) rate among children with acute leukemia seen at a large referral center in Italy. The intervention consisted of 9 in-person sessions for education and practice using mannequins and children.One hundred and twenty caregivers agreed to participate in the initiative. One hundred and five (87.5%) completed the training, 5 (4.1%) withdrew after the first session, and 10 (8.3%) withdrew during practical sessions. After educational intervention, the overall CLABSI rate was reduced by 46% (from 6.86 to 3.70/1000 CL-days). CLABSI rate was lower in children whose caregivers completed the training (1.74/1000 CL-days, 95% CI 0.43-6.94) compared with those who did not receive any training (12.2/1000 CL-days, 95% CI 7.08-21.0, P < 0.05) or were in-training (3.96/1000 CL-days, 95% CI 1.98-7.91) at the time of infection.Caregiver training in CL management, applied within a multifaceted QI approach, reduced the rate of CLABSI in children with acute leukemia. Specific training and active involvement of caregivers in CL management may be effective to reduce CLABSI in high-risk children.
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