Reduced central line infection rates in children with leukemia following caregiver training: A quality improvement

Andrea Lo Vecchio1, Joshua K Schaffzin, Eliana Ruberto

  • 1Department of Translational Medical Science, Section of Pediatrics, University of Naples Federico II, Naples, Italy Division of Infectious Diseases, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio Onco-Hematology Unit, Santobono-Pausilipon Children's Hospital Department of Pediatrics, Azienda Ospedaliera Universitaria Federico II, Naples, Italy.

Medicine
|June 24, 2016
PubMed

Insights

Caregiver education on central-line (CL) management significantly reduced central-line-associated bloodstream infections (CLABSI) in children with acute leukemia. This quality improvement initiative demonstrated the effectiveness of training high-risk pediatric patients’ caregivers.

Area of Science:

  • Pediatric Oncology
  • Infectious Diseases
  • Quality Improvement Science

Background:

  • Infections pose a significant threat to children with acute leukemia, with central-line devices increasing their risk of serious infections.
  • Central-line-associated bloodstream infections (CLABSI) are a major concern in immunocompromised pediatric populations.

Purpose of the Study:

  • To evaluate the impact of caregiver education on central-line management on the CLABSI rate in children with acute leukemia.
  • To assess the effectiveness of a quality improvement intervention focused on caregiver training.

Main Methods:

  • A quality improvement project involving 9 in-person education and practice sessions for caregivers of children with acute leukemia.
  • Training utilized mannequins and direct patient scenarios to enhance CL management skills.
  • Data on CLABSI rates were collected before and after the caregiver education intervention.

Main Results:

  • The overall CLABSI rate decreased by 46% (from 6.86 to 3.70 per 1000 central-line days) post-intervention.
  • Children whose caregivers completed training had significantly lower CLABSI rates (1.74/1000 CL-days) compared to those without training (12.2/1000 CL-days).
  • Caregivers in training also showed a lower CLABSI rate (3.96/1000 CL-days) than those not trained.

Conclusions:

  • Caregiver education in central-line management, as part of a quality improvement initiative, effectively reduced CLABSI rates in pediatric acute leukemia patients.
  • The active involvement and specific training of caregivers are crucial for minimizing CLABSI risk in high-risk children.
  • This approach highlights the potential of empowering caregivers to improve patient safety and outcomes.

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