Related Experiment Video

Updated: Mar 19, 2026

EPA Method 1615. Measurement of Enterovirus and Norovirus Occurrence in Water by Culture and RT-qPCR. II. Total Culturable Virus Assay
11:09

EPA Method 1615. Measurement of Enterovirus and Norovirus Occurrence in Water by Culture and RT-qPCR. II. Total Culturable Virus Assay

Published on: September 11, 2016

9.3K

Enteroviruses and Parechoviruses

James J Dunn1

  • 1Department of Pathology, Texas Children's Hospital, Houston, TX 77030.

Microbiology Spectrum
|June 24, 2016
PubMed

Insights

Enteroviruses and human parechoviruses cause prevalent infections, especially in neonates. Molecular diagnostics are key for identifying these viruses, crucial for patient prognosis and treatment.

Area of Science:

  • Virology
  • Infectious Diseases
  • Neonatal Medicine

Background:

  • Enteroviruses and human parechoviruses are common viral pathogens with significant impact, particularly in neonates.
  • B-cell immunodeficiencies increase risk for severe, often fatal, enteroviral meningoencephalitis.
  • Transplant recipients and cancer patients face risks of severe enterovirus infections, including disseminated disease.

Purpose of the Study:

  • To highlight the prevalence and clinical significance of enterovirus and human parechovirus infections.
  • To emphasize the diagnostic challenges and importance of accurate laboratory identification.
  • To underscore the role of diagnostics in patient management and prognosis.

Main Methods:

  • Review of current diagnostic approaches for enterovirus and human parechovirus.
  • Discussion of molecular diagnostic techniques, including nucleic acid detection.
  • Analysis of limitations in routine diagnostic methods.

Main Results:

  • Molecular diagnostics are the primary method for detecting enterovirus and human parechovirus.
  • Standard enterovirus nucleic acid tests do not detect human parechoviruses.
  • Accurate laboratory diagnosis is critical for patient outcomes.

Conclusions:

  • Effective management of enterovirus and human parechovirus infections relies on precise laboratory diagnosis.
  • Distinguishing between these viral infections is essential for appropriate clinical care.
  • Advancements in molecular diagnostics are vital for improving patient prognosis.

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