Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Bacterial Gastroenteritis01:18

Bacterial Gastroenteritis

5
Bacterial gastroenteritis, characterized by diarrhea, abdominal cramps, and vomiting, is often caused by ingestion of contaminated food or water and is frequently associated with pathogenic Escherichia coli strains. These microbes exploit two principal mechanisms to inflict disease.Shiga toxin–producing E. coli, also referred to as STEC—notably O157:H7—release Shiga toxins that target ribosomes, blocking protein synthesis. The B subunit of the toxin binds the host glycolipid...
5
Gastrointestinal Motility Disorders01:20

Gastrointestinal Motility Disorders

1.5K
Gastrointestinal or GI motility disorders are characterized by irregular gastrointestinal tract movements, disrupting food transit from the mouth to the anus. They are caused by damage or dysfunction in gut muscles or nerves. These disorders can cause symptoms such as severe constipation, diarrhea, abdominal pain, and swallowing difficulties. Disorders can affect any segment of the GI tract and range widely in severity, from common conditions like GERD to life-threatening conditions like...
1.5K
Other Disorders of Digestive System01:30

Other Disorders of Digestive System

1.7K
The gastrointestinal tract is susceptible to various disorders. If the lower esophageal sphincter is damaged, stomach acid can flow back into the esophagus, causing irritation and inflammation of the lining. This condition is called gastroesophageal reflux disease (known as heartburn) and may cause chest pain and difficulty swallowing. In the stomach, prolonged use of nonsteroidal anti-inflammatory drugs like aspirin, chronic alcohol consumption, bacterial infections such as Helicobacter...
1.7K
Microbiota of the Stomach and Small Intestine01:27

Microbiota of the Stomach and Small Intestine

1
The human gastrointestinal (GI) tract is characterized by distinct physicochemical conditions that shape its microbial communities. Among these, the stomach presents a particularly challenging environment for microbial colonization due to its highly acidic pH, ranging from 1 to 3. This extreme acidity effectively limits microbial density. However, certain acid-tolerant microorganisms are capable of surviving in this niche. Notably, Helicobacter pylori can colonize the gastric mucosa,...
1
Drugs Affecting GI Tract Motility: Antimicrobials as Antidiarrheal Agents01:18

Drugs Affecting GI Tract Motility: Antimicrobials as Antidiarrheal Agents

526
Acute diarrhea, a common gastrointestinal disturbance, is characterized by the rapid evacuation of fluid stools, leading to an excessive weight in fluid. This condition typically arises from disorders affecting intestinal water and electrolyte transport. It can be triggered by an increased osmotic load within the intestine, excessive secretion of electrolytes and water, mucosal exudation of protein and fluid, or altered intestinal motility. The primary risks of acute diarrhea are dehydration...
526
Assessment of the Gastrointestinal System I: Subjective Data01:17

Assessment of the Gastrointestinal System I: Subjective Data

772
Assessing the gastrointestinal (GI) system is a complex process that begins with collecting subjective data. This data, collected through patient interviews, provides crucial insights into the patient's health history, perception patterns, and lifestyle habits, all contributing significantly to GI health.
Health History
The initial step in assessing the GI system is obtaining a comprehensive health history. This includes inquiring about the patient's history or presence of problems...
772

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Pervasive Intestinal Carriage with Multiple Species of Extended-Spectrum Cephalosporin-Resistant Enterobacterales in Children Admitted for Severe Acute Malnutrition at a Tertiary Hospital in Malawi.

The American journal of tropical medicine and hygiene·2026
Same author

Escherichia coli ST131 Drives Carbapenem Use for E. Coli Bloodstream Infections.

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America·2026
Same author

Risk Factors for Community Colonization With Extended-Spectrum Cephalosporin-Resistant Enterobacterales Among People Living With HIV in Botswana.

Open forum infectious diseases·2026
Same author

Susceptibility reporting and antibiotic prescribing for UTIs in the inpatient setting: a nudge toward improved stewardship.

Antimicrobial stewardship & healthcare epidemiology : ASHE·2025
Same author

Multicenter evaluation of the QuickMIC<sup>®</sup> rapid AST system in clinical practice: impact on turnaround time compared to routine AST systems.

European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology·2025
Same author

Evaluation of the user experience for a point of care molecular test for causes of vaginitis.

BMC infectious diseases·2025
Same journal

Dietary supplementation with fermented compound Chinese herbal medicine reshapes the gastrointestinal microbiota and enhances growth in suckling lambs.

Microbiology spectrum·2026
Same journal

Prevalence and genotypic distribution of virulence factor genes and antibiotic susceptibility profiles in clinical <i>Pseudomonas aeruginosa</i> isolates from a public hospital in Nanyang, China.

Microbiology spectrum·2026
Same journal

Ammonium ion concentration-dependent production of extracellular polysaccharides from glycerol by an oleaginous yeast: visualization of the producer cells.

Microbiology spectrum·2026
Same journal

Characterization of <i>Klebsiella</i> phages PMBT12, PMBT63, and PMBT64 with functional insights into a Hoc-like, mucin-interacting protein of phage PMBT63.

Microbiology spectrum·2026
Same journal

Immune evasion, infectivity, and membrane fusion of SARS-CoV-2 variants LP.8.1.1, XEC.25.1, XFG, and NB.1.8.1.

Microbiology spectrum·2026
Same journal

Metabolomics profiling reveals changes in peptidoglycan and redox metabolism between ancient and modern <i>Mycobacterium tuberculosis</i>.

Microbiology spectrum·2026
See all related articles

Related Experiment Video

Updated: Mar 19, 2026

Enteric Bacterial Invasion Of Intestinal Epithelial Cells In Vitro Is Dramatically Enhanced Using a Vertical Diffusion Chamber Model
10:52

Enteric Bacterial Invasion Of Intestinal Epithelial Cells In Vitro Is Dramatically Enhanced Using a Vertical Diffusion Chamber Model

Published on: October 22, 2013

14.2K

Gastrointestinal Infections.

Kevin Alby1, Irving Nachamkin1

  • 1Department of Pathology and Laboratory Medicine, University of Pennsylvania, Perelman School of Medicine, Philadelphia, PA 19104.

Microbiology Spectrum
|June 24, 2016
PubMed
Summary
This summary is machine-generated.

Gastrointestinal infections in immunocompromised patients can stem from common pathogens, but these individuals face higher risks. This review covers agents, risk factors, and diagnostics for these infections.

More Related Videos

Adapting Gastrointestinal Organoids for Pathogen Infection and Single Cell Sequencing under Biosafety Level 3 BSL-3 Conditions
07:59

Adapting Gastrointestinal Organoids for Pathogen Infection and Single Cell Sequencing under Biosafety Level 3 BSL-3 Conditions

Published on: September 10, 2021

3.6K
A High-throughput Platform for the Screening of Salmonella spp./Shigella spp.
06:55

A High-throughput Platform for the Screening of Salmonella spp./Shigella spp.

Published on: November 7, 2018

9.5K

Related Experiment Videos

Last Updated: Mar 19, 2026

Enteric Bacterial Invasion Of Intestinal Epithelial Cells In Vitro Is Dramatically Enhanced Using a Vertical Diffusion Chamber Model
10:52

Enteric Bacterial Invasion Of Intestinal Epithelial Cells In Vitro Is Dramatically Enhanced Using a Vertical Diffusion Chamber Model

Published on: October 22, 2013

14.2K
Adapting Gastrointestinal Organoids for Pathogen Infection and Single Cell Sequencing under Biosafety Level 3 BSL-3 Conditions
07:59

Adapting Gastrointestinal Organoids for Pathogen Infection and Single Cell Sequencing under Biosafety Level 3 BSL-3 Conditions

Published on: September 10, 2021

3.6K
A High-throughput Platform for the Screening of Salmonella spp./Shigella spp.
06:55

A High-throughput Platform for the Screening of Salmonella spp./Shigella spp.

Published on: November 7, 2018

9.5K

Area of Science:

  • Gastroenterology
  • Immunology
  • Infectious Diseases

Background:

  • Immunocompromised hosts are susceptible to gastrointestinal infections.
  • These infections can be caused by common or unusual pathogens.
  • Disease severity and risk are elevated in immunocompromised individuals.

Purpose of the Study:

  • To review common and uncommon agents causing gastrointestinal infections in immunocompromised patients.
  • To identify specific risk factors predisposing these patients to infection.
  • To outline diagnostic approaches for detecting gastrointestinal infections in this population.

Main Methods:

  • Literature review of gastrointestinal infections in immunocompromised hosts.
  • Analysis of common bacterial, viral, fungal, and parasitic agents.
  • Discussion of risk factors and diagnostic strategies.

Main Results:

  • Common pathogens pose a significant threat to immunocompromised patients.
  • Certain pathogens may exclusively affect immunocompromised individuals.
  • Increased risk for infection and disease severity is a key concern.

Conclusions:

  • Understanding causative agents is crucial for managing gastrointestinal infections in the immunocompromised.
  • Identifying risk factors aids in prevention and early detection.
  • Comprehensive diagnostic approaches are essential for effective treatment.