Related Experiment Video
Updated: Jul 28, 2026
Single Cell Measurement of Dopamine Release with Simultaneous Voltage-clamp and Amperometry
Published on: November 21, 2012
Ag-CNT Architectures for Attomolar Dopamine Detection and 100-Fold Fluorescence Enhancements with Cellphone-Based
Pradeep Kumar Badiya1, Venkatesh Srinivasan1, Tejkiran Pindi Jayakumar1
1Plasmonics Laboratory, Department of Chemistry, Sri Sathya Sai Institute of Higher Learning, Prasanthi Nilayam, Anantapur, Andhra Pradesh, 515134, India.
Abstract:
We report cellphone-based detection of dopamine with attomolar sensitivity in clinical samples with the use of a surface plasmon-coupled emission (SPCE) platform. To this end, silver-coated carbon nanotubes were used as spacer and cavity materials on SPCE substrates to obtain up to 100-fold fluorescence enhancements. The presence of silver on the carbon nanotubes helped to overcome fluorescence quenching arising due to π-π interactions between the carbon nanotube and rhodamine 6G. The competing adsorption of dopamine versus rhodamine 6G on graphene oxide was utilized to develop this sensing platform.
