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Published on: September 29, 2016
Tandem Catalysis of an Aldol-'Click' Reaction System within a Molecular Hydrogel
Marco Araújo1, Iván Muñoz Capdevila2, Santiago Díaz-Oltra3
1Departament de Química Inorgànica i Orgànica, Universitat Jaume I, 12071 Castelló, Spain. cerqueir@uji.es.
Abstract:
A heterogeneous supramolecular catalytic system for multicomponent aldol-'click' reactions is reported. The copper(I) metallohydrogel functionalized with a phenyltriazole fragment was able to catalyze the multicomponent reaction between phenylacetylene, p-nitrobenzaldehyde, and an azide containing a ketone moiety, obtaining the corresponding aldol products in good yields. A possible mechanistic pathway responsible for this unexpected catalytic behavior has been proposed.
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