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Exploiting the Biosynthetic Potential of Type III Polyketide Synthases

Yan Ping Lim1,2, Maybelle K Go3,4, Wen Shan Yew5,6

  • 1Department of Biochemistry, Yong Loo Lin School of Medicine, National University of Singapore, 8 Medical Drive, Singapore 117597, Singapore. bchlimy@nus.edu.sg.

Molecules (Basel, Switzerland)
|June 25, 2016
PubMed
Summary

This review explores type III polyketide synthases (PKSs), enzymes crucial for creating diverse polyketides. Engineering these PKSs offers a pathway to novel compounds for drug discovery.

Keywords:
chalcone synthasepolyketideprecursor-directed combinatorial biosynthesisstilbene synthasesynthetic enzymology

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