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Children and Adolescents with Perinatal HIV-1 Infection: Factors Associated with Adherence to Treatment in the

Maria Letícia Santos Cruz1, Claudete A Araújo Cardoso2, Mariana Q Darmont3

  • 1Infectious Diseases Department, Hospital Federal dos Servidores do Estado, Rua Sacadura Cabral 178, Rio de JaneiroRJ 20221-161, Brazil. mleticia@diphse.com.br.

International Journal of Environmental Research and Public Health
|June 25, 2016
PubMed

Insights

Caregivers

Area of Science:

  • Pediatric Infectious Diseases
  • Public Health
  • Social Sciences

Background:

  • Combination antiretroviral therapy (cART) adherence in children living with HIV (CALHIV) is complex.
  • Family dynamics, healthcare interactions, and socioeconomic factors influence adherence.

Purpose of the Study:

  • To analyze individual, institutional, and social factors affecting caregivers' role in CALHIV treatment adherence.
  • To identify key determinants for improving adherence in pediatric HIV care.

Main Methods:

  • Semi-structured interviews and questionnaires.
  • Study involved 69 caregivers at pediatric AIDS services across five Brazilian regions.
  • Qualitative and quantitative data analysis of caregiver perspectives.

Main Results:

  • Adherent caregivers demonstrated better diagnosis and treatment acceptance.
  • Reduced experiences of discrimination and social isolation linked to AIDS-related stigma were observed.
  • Belief in treatment efficacy and optimism about CALHIV's future correlated with adherence.

Conclusions:

  • Caregiver adherence is influenced by a complex interplay of personal beliefs, social support, and healthcare system engagement.
  • Interventions must address stigma, promote treatment optimism, and support families holistically.
  • Improving adherence requires a multi-faceted approach considering individual, institutional, and societal factors.

Keywords:
HIV infectionadolescentscaregiverschildrenpatient adherencevulnerability

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