Related Experiment Video
Updated: Mar 19, 2026
Routine Screening Method for Microparticles in Platelet Transfusions
Published on: January 31, 2018
Predictive value of platelet-to-lymphocyte ratio in exacerbation of chronic obstructive pulmonary disease
Gülistan Karadeniz1, Serir Aktoğu1, Onur Fevzi Erer1
1Dr Suat Seren Chest Disease & Surgery Training & Research Hospital, Department of Pulmonology, Izmir, Turkey.
Aim:
We aimed to assess the platelet-to-lymphocyte ratio (PLR) and platelet parameters in patients with chronic obstructive pulmonary disease (COPD).
Methods:
A total of 60 stable COPD patients, 50 acute exacerbation COPD patients and 50 healthy controls were enrolled in this study.
Results:
The platelet distribution width and PLR were higher and the mean platelet volume was lower in the COPD patients during acute exacerbation compared with the stable patients and controls. The PLR was negatively correlated with the forced expiratory volume in 1 s.
Conclusion:
The PLR may be used as a useful and easily accessible tool for evaluating the ongoing inflammation during stable period and the disease severity during acute exacerbations in COPD patients.
