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Single embryo transfer for all?
Laura M Miller1, Ruth Hodgson2, Tze Yoong Wong2
1Fertility Plus, Reproductive Endocrinology and Fertility Unit of National Women's, Greenlane Clinical Centre, Auckland, New Zealand. lmiller@adhb.govt.nz.
Summary
Selective single embryo transfer (SET) is becoming standard in in vitro fertilisation (IVF) due to technological advances. This study evaluates if current confidence in SET supports making it a mandatory procedure for all patients.
Area of Science:
- Reproductive medicine
- Embryology
- Clinical obstetrics and gynecology
Background:
- Historically, multiple embryo transfer was standard in in vitro fertilisation (IVF) to ensure live birth rates.
- Technological advancements in IVF have facilitated a shift towards selective single embryo transfer (SET).
Purpose of the Study:
- To assess the current confidence level in single embryo transfer (SET) as a standalone procedure.
- To determine if SET can be recommended as a mandatory practice in assisted reproductive technology.
Main Methods:
- Review of current literature on SET success rates.
- Analysis of live birth data comparing SET with multiple embryo transfer.
- Evaluation of technological improvements impacting embryo viability and selection.
Main Results:
- SET success rates are increasingly comparable to multiple embryo transfers.
- Technological improvements have enhanced embryo selection and viability.
- Potential risks associated with multiple pregnancies are significantly reduced with SET.
Conclusions:
- Confidence in SET is growing due to improved IVF technologies and outcomes.
- SET is a viable and potentially preferable option, warranting consideration for mandatory implementation.
- Further research may be needed to establish universal guidelines for mandatory SET.

