Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

The Arch of Aorta01:10

The Arch of Aorta

2.2K
The coronary arteries, originating from the ascending aorta, bifurcate from two sinuses located within the ascending aorta. Positioned just above the aortic semilunar valve, these sinuses house essential aortic baroreceptors and chemoreceptors, crucial for maintaining cardiac function. The left coronary artery and the right coronary artery branch off from the left posterior and anterior aortic sinuses, respectively.
Encircling the heart, the coronary arteries form a ring-like structure before...
2.2K
Arteries of the Head and Neck01:26

Arteries of the Head and Neck

4.1K
The human body's intricate network of arteries ensures that every organ system receives the necessary oxygen and nutrients for optimal function. The arterial network in the head and neck region is particularly complex, providing vital blood flow to the brain, eyes, and other critical structures. Prominent arteries in this region include the internal carotid arteries and the vertebral arteries.
The internal carotid arteries supply blood to the anterior portion of the cerebrum. They enter the...
4.1K
Anastomoses01:19

Anastomoses

3.5K
In human anatomy, anastomosis refers to a connection or opening between two things, particularly between blood vessels or other tubular structures. The term is derived from the Greek term 'anastomosis,' which means 'outlet' or 'opening.' This natural network of connections plays a critical role in the survival and functionality of the human body.
Anastomoses can be formed at arterial, venous, and lymphatic vessels.
Arterial Anastomosis: These occur between arteries. They...
3.5K
Aneurysm I: Introduction01:30

Aneurysm I: Introduction

591
An aortic aneurysm is a localized outpouching or dilation at a weak point in the artery wall. It may involve different parts of the aorta, such as the abdominal aorta, aortic arch, or thoracic aorta.Etiological factorsSeveral disorders are associated with aortic aneurysms.Congenital causes, such as primary connective tissue disorders like Marfan syndrome, impact the integrity and strength of connective tissues, notably affecting the aorta. Marfan syndrome is a genetic disorder that specifically...
591
Aneurysm II: Clinical Manifestations and Diagnostic Studies01:21

Aneurysm II: Clinical Manifestations and Diagnostic Studies

486
Thoracic, aortic arch and abdominal aneurysms are significant vascular conditions that can present with various clinical manifestations and lead to serious complications. Understanding these manifestations and the appropriate diagnostic studies is essential for effective management and treatment.Thoracic Aortic AneurysmsThoracic aortic aneurysms often remain asymptomatic until they reach a size that impinges on adjacent structures. They typically cause deep, diffuse chest pain that radiates to...
486
Aneurysm III: Interprofessional Care01:26

Aneurysm III: Interprofessional Care

438
Aneurysm management involves either conservative medical therapy or surgical intervention, depending on the size and symptoms of the aneurysm. Conservative management is generally reserved for smaller, asymptomatic aneurysms, while larger or symptomatic aneurysms often necessitate surgical repair.Conservative Medical TherapyFor small, asymptomatic aneurysms, particularly abdominal aortic aneurysms (AAA) less than 5.5 centimeters in diameter, conservative medical therapy is recommended. This...
438

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Intracranial Atherosclerotic Disease Distribution Across Circle of Willis Segments: Insights from CREST-H.

AJNR. American journal of neuroradiology·2026
Same author

Taking a Closer Look at the Role of Inflammation in Cerebrovascular Diseases.

Stroke·2026
Same author

Systemic Cardiovascular Factors and Outcomes in Dural Arteriovenous Fistulas: Insights From the CONDOR Registry.

Stroke·2026
Same author

Longitudinal MRI and Perfusion Changes in Cerebral Proliferative Angiopathy.

Stroke·2026
Same author

Recurrence of Angiographically Cured AVMs: Influence of Age, Angioarchitecture, and Hemorrhagic Presentation and Implications for Follow-Up.

Stroke (Hoboken, N.J.)·2026
Same author

Relationship Between Degree of Stenosis and Time-to-Peak Delay in High Grade Asymptomatic Carotid Artery Disease.

Stroke·2026

Related Experiment Video

Updated: Mar 19, 2026

Comprehensive Endovascular and Open Surgical Management of Cerebral Arteriovenous Malformations
14:58

Comprehensive Endovascular and Open Surgical Management of Cerebral Arteriovenous Malformations

Published on: October 20, 2017

10.4K

Aneurysms Associated with Brain Arteriovenous Malformations.

S K Rammos1, B Gardenghi2, C Bortolotti3

  • 1From the Department of Neurosurgery (S.K.R.), Arkansas Neuroscience Institute, Little Rock, Arkansas.

AJNR. American Journal of Neuroradiology
|June 25, 2016
PubMed
Summary

This review examines the frequent co-occurrence of brain arteriovenous malformations and intracranial aneurysms. It explores how advanced imaging improves detection, the increased bleeding risks these combined lesions pose, and the resulting complexities for surgical and interventional treatment planning.

Keywords:
neurovascular diseasecerebral angiographyhemorrhagic riskvascular neurosurgery

Frequently Asked Questions

More Related Videos

Microsurgical Clip Obliteration of Middle Cerebral Aneurysm Using Intraoperative Flow Assessment
18:50

Microsurgical Clip Obliteration of Middle Cerebral Aneurysm Using Intraoperative Flow Assessment

Published on: September 25, 2009

14.1K
Isolation and Cannulation of Cerebral Parenchymal Arterioles
09:49

Isolation and Cannulation of Cerebral Parenchymal Arterioles

Published on: May 23, 2016

12.7K

Related Experiment Videos

Last Updated: Mar 19, 2026

Comprehensive Endovascular and Open Surgical Management of Cerebral Arteriovenous Malformations
14:58

Comprehensive Endovascular and Open Surgical Management of Cerebral Arteriovenous Malformations

Published on: October 20, 2017

10.4K
Microsurgical Clip Obliteration of Middle Cerebral Aneurysm Using Intraoperative Flow Assessment
18:50

Microsurgical Clip Obliteration of Middle Cerebral Aneurysm Using Intraoperative Flow Assessment

Published on: September 25, 2009

14.1K
Isolation and Cannulation of Cerebral Parenchymal Arterioles
09:49

Isolation and Cannulation of Cerebral Parenchymal Arterioles

Published on: May 23, 2016

12.7K

Area of Science:

  • Neurovascular pathology within intracranial arteriovenous malformations research
  • Diagnostic neuroradiology and clinical neurosurgery

Background:

The clinical intersection of vascular anomalies remains a complex challenge in modern neurology. No prior work had fully resolved the exact frequency of these co-occurring lesions. Prior research has shown that these vascular abnormalities appear together more often than chance alone would predict. That uncertainty drove clinicians to seek better detection methods for high-risk patients. It was already known that identifying these dual pathologies is vital for patient safety. This gap motivated a deeper look into the radiological features of these combined vascular conditions. Prior studies often lacked a unified framework for understanding their shared clinical impact. This review addresses the need for a comprehensive assessment of these interconnected vascular threats.

Purpose Of The Study:

The aim of this review is to synthesize the current understanding of intracranial aneurysms associated with arteriovenous malformations. This study addresses the diagnostic and therapeutic complexities faced by neurovascular specialists. The authors seek to clarify the clinical significance of these co-occurring vascular anomalies. They investigate how modern imaging techniques have changed the detection landscape for these patients. The motivation stems from the increased risk of hemorrhage associated with these dual lesions. By examining existing classification systems, the researchers provide a guide for clinical practice. This work intends to offer a clear perspective on the natural history of these combined conditions. The review ultimately serves to inform better management strategies for complex neurovascular cases.

Main Methods:

The review approach centers on synthesizing existing literature regarding the co-occurrence of vascular lesions. Investigators evaluated current classification systems to organize diverse clinical presentations. They examined technical reports detailing the application of high-resolution imaging in clinical settings. The team performed a systematic assessment of radiological findings associated with these dual pathologies. They analyzed published data to determine the impact of these lesions on patient outcomes. This methodology focuses on integrating findings from neurosurgical and neuroradiological studies. The authors prioritized peer-reviewed evidence to ensure the reliability of their clinical synthesis. This structured evaluation provides a clear overview of the current state of knowledge in the field.

Main Results:

Key findings from the literature indicate that these vascular lesions occur together at a frequency exceeding individual lesion rates. The authors report that improved diagnostic capabilities have led to higher detection levels. They observe that 3D angiography provides superior detail for identifying these complex vascular connections. The literature suggests that the presence of an aneurysm correlates with a greater risk of initial hemorrhage. Furthermore, patients with both conditions face a higher probability of rehemorrhage compared to those with isolated lesions. The synthesis shows that these combined pathologies present significant hurdles for neurointerventional specialists. The data confirms that the natural history for these patients is generally less favorable. These results highlight the necessity of precise imaging for effective therapeutic decision-making.

Conclusions:

The authors propose that these combined vascular lesions significantly alter the clinical trajectory for affected individuals. They suggest that the presence of an aneurysm increases the likelihood of initial bleeding events. The review highlights that therapeutic decisions require careful balancing of risks versus potential benefits. Clinicians must consider the specific location and morphology of both lesions during planning. The researchers emphasize that modern imaging techniques are vital for accurate pre-treatment assessment. They argue that the natural history of these patients is often less favorable than those with isolated malformations. The team concludes that management strategies should be tailored to the unique vascular anatomy of each case. These findings underscore the necessity of a multidisciplinary approach to complex neurovascular care.

The researchers propose that these vascular lesions increase the risk of hemorrhage at presentation. This elevated danger is compared to patients who possess only a single malformation, suggesting that dual pathology leads to a more unfavorable clinical history.

The authors highlight that 3D and superselective conventional angiography are the primary tools for detection. These advanced imaging methods allow for superior visualization compared to older, standard diagnostic techniques.

The authors suggest that the specific location of the aneurysm relative to the malformation is a technical necessity for planning. Understanding this spatial relationship helps surgeons determine if the aneurysm requires direct intervention or if treating the malformation suffices.

The researchers utilize clinical data and radiological findings to synthesize their review. This evidence-based approach helps categorize the different types of lesions, providing a structured framework for practitioners to evaluate complex cases.

The authors note that the incidence of these lesions is higher than expected based on the frequency of each condition alone. This phenomenon suggests a potential shared underlying vascular pathology that warrants further investigation.

The researchers imply that these findings should guide future treatment protocols. They suggest that a multidisciplinary team, including neurosurgeons and radiologists, is required to address the therapeutic challenges posed by these dual vascular anomalies.