Related Experiment Video
Updated: Mar 19, 2026

Modified Experimental Conditions for Noise-Induced Hearing Loss in Mice and Assessment of Hearing Function and Outer Hair Cell Damage
Published on: February 10, 2023
Effects of Hyperlipidemia on Noise Induced Hearing Loss (NIHL)
Afsaneh Doosti1, Yones Lotfi2, Enayatollah Bakhshi3
1Audiology Department, Shiraz University of Medical Sciences, Shiraz, Iran.
Abstract:
Likelihood of developing noise induced hearing loss (NIHL) is affected by some factors such as genes, nutrition and healthy hearing habits. We investigated this study to determine the effect of hyperlipidemia on NIHL. In a case-control study, 144 workers who exposed to continuous noise more than 85 dBA (88-89 dBA) from a textile factory in Tehran were examined. Serum Blood test results as index for dyslipidemi, were collected and audiometry tests were carried out to analyze the association of hyperlipidemian and NIHL. The mean ±SD of Cholesterol level for NIHL and control were 188.19 (28.46) and 159.00 (26.66) mg/dL respectively. Also the mean ±SD of Triglyceride level for NIHL and control were 203.75 (53.92) and 105.00 (30.50) mg/dL consecutively. After adjusting odds ratio (OR) for NIHL, only hypertriglyceridemia had association with NIHL. (aOR = 1.07; 95 % CI 1.04-1.10), and there wasn't any relation between hypercholestomia and NIHL (aOR = 1.02; 95 % CI 0.99-1.05). Workers with hypertriglyceridemia are at increased risk for NIHL. In factories with elevated noise levels, besides hearing conservation programs, attention to blood serum level of workers and healthy diet are proposed to help in preserving hearing threshold.
Related Concept Videos
Lipid-Lowering Drugs: Statins and Miscellaneous Agents
Blood Studies for Cardiovascular System III: Serum Lipid Profile
Serum lipids are fats and fatty substances in the blood and are crucial for various bodily functions, including energy storage, cellular structure, and hormone production. Serum lipids consist of cholesterol, triglycerides, and phospholipids.
Cholesterol is a soft, fat-like substance found in all body cells. It is crucial for producing hormones, vitamin D, and substances that aid...
Overview of Lipid Metabolism
Lipolysis: The Breakdown of Lipids:
Lipolysis is the process of breaking down lipids, particularly triglycerides, into glycerol and fatty acids. This process typically occurs in the adipose tissue and is triggered by various hormones, including glucagon and...

