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Filling a GAP-An Optimized Probe for ER Ca(2+) Imaging In Vivo
Roland Malli1, Emrah Eroglu1, Markus Waldeck-Weiermair1
1Institute of Molecular Biology and Biochemistry, Center of Molecular Medicine, Medical University of Graz, Harrachgasse 21/III, 8010 Graz, Austria.
Cell Chemical Biology
|June 25, 2016
Abstract
None:
In this issue of Cell Chemical Biology, Navas-Navarro et al. (2016) demonstrate that fusion of engineered derivatives of the long-known jellyfish proteins green fluorescent protein (GFP) and aequorin yield optimized genetically encoded fluorescent probes for detecting Ca(2+) signals within the endoplasmic reticulum (ER) of living animals.
