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Optimizing Extracellular Vesicle Delivery Using a Core-Sheath 3D-Bioprinted Scaffold for Chronic Wound Management
Published on: February 28, 2025
Seminal vesicle sperm aspiration from wounded warriors
Mae Wu Healy1, Belinda J Yauger1, Aidita N James2
1Division of Reproductive Endocrinology and Infertility, Department of Obstetrics and Gynecology, Walter Reed National Military Medical Center, Bethesda, Maryland; Program in Reproductive and Adult Endocrinology, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Maryland.
Seminal vesicle sperm aspiration (SVSA) offers a viable method for retrieving sperm in wounded warriors with severe genital injuries, enabling future fertility options through assisted reproductive technology (ART). This technique is a promising solution for preserving reproductive potential in trauma patients.
Area of Science:
- Reproductive Medicine
- Urology
- Trauma Surgery
Background:
- Severe genital and testicular injuries pose significant challenges to fertility in wounded warriors.
- Assisted reproductive technology (ART) offers potential solutions for fertility preservation.
Purpose of the Study:
- To evaluate the efficacy of seminal vesicle sperm aspiration (SVSA) for sperm retrieval in wounded warriors with severe genital injuries.
- To assess the feasibility of cryopreserving retrieved sperm for future ART cycles.
Main Methods:
- Retrospective case series involving six wounded warriors with lower extremity, pelvic, and genital injuries.
- SVSA performed within 5-12 days of injury.
- Analysis of retrieved sperm parameters (volume, concentration, motility) and cryopreservation.
Main Results:
- Sperm were successfully retrieved via SVSA in all six patients.
- Cryopreserved sperm were used in two in vitro fertilization/intracytoplasmic sperm injection (IVF/ICSI) cycles.
- One cycle resulted in a live birth, demonstrating the potential of SVSA for achieving pregnancy.
Conclusions:
- SVSA is a feasible and effective method for sperm retrieval in wounded warriors with extensive genital injuries.
- This technique provides a crucial option for fertility preservation and future ART in this patient population.
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