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Donor T Cells May Enhance Immunotherapy

    Cancer Discovery
    |June 26, 2016
    PubMed

    A proof-of-principle study demonstrates that T cells from healthy donors recognize many tumor neoantigens overlooked by a patient's own immune system. Outsourcing neoantigen-induced immune reactivity to donor T cells could be a feasible way to bolster patients' response to immunotherapy.

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