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Updated: Mar 18, 2026
11:39
The Goeckerman Regimen for the Treatment of Moderate to Severe Psoriasis
Published on: July 11, 2013
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Expert Recommendations on Treating Psoriasis in Special Circumstances (Part II)
J M Carrascosa1, M Galán2, R de Lucas3
1Servei de Dermatologia, Hospital Universitari GermansTrias i Pujol, Universitat Autònoma de Barcelona, Badalona, Barcelona, España.
Actas Dermo-Sifiliograficas
|June 27, 2016
Summary
Expert dermatologists reached consensus on treating moderate to severe psoriasis, offering guidance for pediatric cases, biologic safety, and improving drug survival. This structured opinion aids clinical decisions where evidence is limited.
Area of Science:
- Dermatology
- Clinical Practice Guidelines
- Evidence-Based Medicine
Background:
- Psoriasis management presents challenges due to insufficient evidence in specific clinical scenarios.
- Key areas of uncertainty include pediatric psoriasis, biologic-related infection risks, and treatment in difficult locations.
Framework:
- A Delphi method expert panel addressed 5 critical areas of psoriasis management.
- The panel comprised dermatologists specializing in psoriasis treatment.
Implementation:
- Consensus was achieved on 70.9% of analyzed items, with agreement on monitoring pediatric psoriasis patients for BMI, comorbidities, and quality of life.
- Methotrexate was identified as the preferred systemic treatment, and etanercept as the preferred biologic for pediatric psoriasis.
- Strategies to enhance biologic drug survival include individualized dosing, continuous therapy, and combination treatments.
Implications:
- The Dermatology Quality of Life Index is recommended for assessing treatment effectiveness and guiding clinical decisions.
- Expert consensus provides valuable guidance for managing psoriasis in complex clinical situations with limited data.
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