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Published on: October 31, 2012
Generation of human control iPS cell line CHOPWT10 from healthy adult peripheral blood mononuclear cells
Jean Ann Maguire1, Alyssa L Gagne1, Chintan D Jobaliya1
1Center for Cellular and Molecular Therapeutics, The Children's Hospital of Philadelphia, United States; Department of Pathology and Laboratory Medicine, The Children's Hospital of Philadelphia, University of Pennsylvania, United States.
Abstract:
The CHOPWT10 iPS cell line was generated to be used as a control for applications such as in differentiation analyses to the three germ layers and derivative tissues. Peripheral blood mononuclear cells (PBMCs) obtained from a healthy adult male were reprogrammed using the non-integrating Sendai virus expressing Oct3/4, Sox2, c-Myc, and Klf4.
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