Spontaneous hematoma in the setting of dual anti-platelet therapy with ticagrelor: A case report
Chunguang Feng1, Linguang Wang1, Lulu Wang1
1Department of Cardiology, Central Hospital of Xuzhou, Xuzhou Institute of Cardiovascular Disease, Xuzhou, Jiangsu 221009, P.R. China.
Insights
Dual anti-platelet therapy (DAPT) with aspirin and ticagrelor may cause spontaneous hematoma in patients post-coronary stenting. This case highlights a potential risk associated with DAPT, necessitating careful patient monitoring.
Area of Science:
- Cardiology
- Vascular Medicine
- Pharmacology
Background:
- A 69-year-old male presented with right scapular pain and a palpable mass.
- The patient had recently undergone coronary artery stenting.
- He was on dual anti-platelet therapy (DAPT) including aspirin and ticagrelor post-procedure.
Purpose of the Study:
- To investigate the cause of spontaneous hematoma in a patient on DAPT after coronary stenting.
- To evaluate the potential link between DAPT and the development of spontaneous hematoma.
Main Methods:
- Clinical presentation and patient history review.
- Ultrasonic inspection for hematoma diagnosis.
- Assessment of medication history, specifically DAPT.
Main Results:
- A spontaneous hematoma was diagnosed under the right scapula via ultrasound.
- Dual anti-platelet therapy (DAPT) with aspirin and ticagrelor was identified as the sole causative factor for the hematoma.
Conclusions:
- Dual anti-platelet therapy (DAPT) may be associated with an increased risk of spontaneous hematoma formation.
- Clinicians should consider DAPT as a potential cause of unexplained hematomas in patients, particularly after cardiovascular interventions.
Abstract:
A 69-year-old male patient was admitted to hospital because a lump was discovered, accompanied with pain lasting 5 h under his right scapula. Two months earlier, he had undergone a double-stent insertion operation due to lesions on the end of the left main coronary artery, the opening of left circumflex artery, and the opening of the anterior descending branch. After the operation, he was administered with dual anti-platelet therapy (DAPT) with aspirin and ticagrelor and was diagnosed with hematoma under his right scapula through ultrasonic inspection. It was established that no other factor, except DAPT, was responsible for his spontaneous hematoma.


