Palliative care needs in patients hospitalized with heart failure (PCHF) study: rationale and design

Ross T Campbell1, Colette E Jackson2, Ann Wright1

  • 1BHF Glasgow Cardiovascular Research Centre University of Glasgow Glasgow Scotland UK.

ESC Heart Failure
|June 28, 2016
PubMed

Insights

This study identifies patient needs for palliative care (PC) in heart failure (HF) to design a future clinical trial. Findings will guide the development of effective PC interventions for HF patients.

Area of Science:

  • Cardiology
  • Palliative Care
  • Clinical Trial Design

Background:

  • Heart failure (HF) patients often have significant unmet palliative care (PC) needs.
  • Designing effective PC interventions for HF requires understanding patient populations and specific needs.
  • Existing research lacks comprehensive data to inform a targeted PC intervention trial in HF.

Purpose of the Study:

  • To gather data for designing a randomized controlled trial (RCT) of a PC intervention in HF.
  • To identify a suitable HF patient population with high, quantifiable PC needs.
  • To define essential components of a PC intervention and relevant trial outcomes for HF.

Main Methods:

  • Prospective cohort study of hospitalized acute decompensated HF patients over 2 years.
  • Screening using B-type natriuretic peptide and echocardiography; comprehensive characterization of HF status, comorbidities, and PC needs.
  • Quantitative assessment of quality of life, mood, symptoms, caregiver burden, and end-of-life care; long-term follow-up for outcomes including mortality.

Main Results:

  • Prevalence and trajectory of PC needs in HF patients will be determined.
  • Methods for identifying HF patients with PC needs will be evaluated.
  • Healthcare utilization patterns associated with PC needs in HF will be estimated.

Conclusions:

  • The study will establish a foundation for an RCT of PC interventions in HF.
  • Data will inform the selection of appropriate patient populations and outcome measures.
  • This research will guide the development of targeted PC interventions to improve HF patient care.
Abstract

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