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A Novel Microfluidic Flow Rate Detection Method Based on Surface Plasmon Resonance Temperature Imaging.

Shijie Deng1, Peng Wang2, Shengnan Liu3

  • 1State Key Laboratory of Precision Measurement Technology and Instruments, Tsinghua University, Beijing 100084, China. dsj11@mails.tsinghua.edu.cn.

Sensors (Basel, Switzerland)
|June 28, 2016
PubMed
Summary

A new method uses surface plasmon resonance (SPR) temperature imaging to detect microfluidic flow rates. This robust sensor technology accurately measures flow in lab-on-chip systems.

Keywords:
microfluidic flow rate detectionsurface plasmon resonancetemperature variation imaging

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Area of Science:

  • Microfluidics
  • Optical Sensing
  • Surface Plasmon Resonance (SPR)

Background:

  • Accurate flow rate monitoring is crucial for microfluidic applications.
  • Existing methods may face limitations in sensitivity, integration, or robustness.

Purpose of the Study:

  • To develop and validate a novel microfluidic flow rate detection method.
  • To leverage surface plasmon resonance (SPR) temperature imaging for flow sensing.

Main Methods:

  • Utilized space-resolved surface plasmon resonance (SPR) imaging to detect flow-induced temperature variations.
  • Performed theoretical simulations and experimental validation.
  • Investigated water flow rates from tens to hundreds of μL/min.

Main Results:

  • Demonstrated a proof of concept for SPR temperature imaging as a flow sensing technique.
  • Successfully detected water flow rates in the range of tens to hundreds of μL/min.
  • The developed sensor exhibited resistance to disturbances.

Conclusions:

  • The proposed SPR temperature imaging method offers a viable approach for microfluidic flow rate detection.
  • The sensor is easily integrable into microfluidic lab-on-chip systems.
  • This technique provides a robust and sensitive solution for microfluidic flow monitoring.