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Microfluidic Buffer Exchange for Interference-free Micro/Nanoparticle Cell Engineering
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Tunnel Dielectrophoresis for Tunable, Single-Stream Cell Focusing in Physiological Buffers in High-Speed Microfluidic
Yu-Chun Kung1, Kuo-Wei Huang1, William Chong1
1Department of Mechanical and Aerospace Engineering, University of California at Los Angeles (UCLA), 14-124 Eng. IV, 420 Westwood Plaza, Los Angeles, CA, 90095-1597, USA.
Small (Weinheim an Der Bergstrasse, Germany)
|June 28, 2016
Abstract:
A novel tunnel dielectrophoresis (TDEP) mechanism is demonstrated for continuously tunable, sheathless, 3D, and single-stream microparticle and cell focusing in high-speed flows in regular physiological buffers. Particles and cells showing negative DEP responses can be focused at the electric field minimum location regardless of their types and sizes.

