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[Guillain-Barre syndrome in children in 2009-2014 years]
Insights
This study observed 21 children with Guillain-Barre syndrome (GBS), finding that most cases involved limb palsy and preceding infections. Treatments like plasmapheresis were effective, and mechanical ventilation was not required.
Area of Science:
- Pediatric Neurology
- Infectious Diseases
Background:
- Guillain-Barre syndrome (GBS) is a leading cause of acute palsy in children, characterized by ascending flaccid paralysis.
- GBS typically presents as a post-infectious, nonfebrile illness with areflexia.
Purpose of the Study:
- To analyze the clinical characteristics and treatment outcomes of pediatric Guillain-Barre syndrome cases over a six-year period.
Main Methods:
- Retrospective analysis of 21 children diagnosed with GBS between 2009 and 2014.
- Evaluation of preceding infections, clinical presentation (limb palsy), and treatment modalities (plasmapheresis, IVIg).
Main Results:
- The study included 21 children (19 boys, 2 girls) with GBS.
- Ninety-five percent (20/21) presented with flaccid limb palsy.
- Sixty-two percent (13/21) had a history of respiratory or digestive infections.
- Eighty-one percent (17/21) were treated with plasmapheresis, and 14% (3/21) with intravenous immunoglobulin, both yielding good outcomes.
Conclusions:
- Mechanical ventilation was not necessary for any pediatric GBS patients during the observation period.
- Plasmapheresis and intravenous immunoglobulin are effective treatments for pediatric GBS.
Introduction:
Guillain-Barre syndrome (GBS) is an acute polyradiculoneuropathy with a variable clinical presentation and is the most common cause of acute palsy in children. The classic presentation is an acute monophasic, nonfebrile, postinfectious illness manifesting as an ascending flaccid palsy with areflexia. Aim. Analysis of children with GBS in 6 years observation.
Material And Methods:
In the present study we describe a population of 21 children (19 boys and 2 girls) with GBS hospitalized in the years 2009-2014 in our department. In this group 20 children (95%) had flaccid palsy of limbs, 13 children (62%) had previous respiratory or digestive infections. 17 (81%) children were treated by plasmapheresis, 3 (14%) by intravenous immunoglobulin with good outcome.
Conclusions:
For 6 years mechanical ventilation was not used in children with GBS.
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