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Cadherin 23-C Regulates Microtubule Networks by Modifying CAMSAP3's Function

Satoe Takahashi1, Vincent J Mui1, Samuel K Rosenberg1

  • 1Department of Otolaryngology - Head and Neck Surgery, Feinberg School of Medicine, Northwestern University, Chicago IL 60611, USA.

Scientific Reports
|June 29, 2016
PubMed
Summary

Cadherin-related 23 (CDH23) directly binds to CAMSAP3/Marshalin, a microtubule (MT) regulator. This interaction, crucial for hearing and vision, modifies MT networks and is impaired by Usher Syndrome mutations.

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