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Updated: Mar 18, 2026

Microsurgical Clip Obliteration of Middle Cerebral Aneurysm Using Intraoperative Flow Assessment
Published on: September 25, 2009
Pipeline Embolization Device for Recurrent Cerebral Aneurysms after Microsurgical Clipping
Nimer Adeeb1, Christoph J Griessenauer1, Justin Moore1
1Neurosurgical Service, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts, USA.
Pipeline embolization device (PED) placement is a safe and effective treatment for recurrent cerebral aneurysms after microsurgical clipping. This approach offers a feasible alternative to reoperation, achieving complete occlusion without associated morbidity or mortality.
Area of Science:
- Neurosurgery
- Interventional Neurology
- Vascular Neurology
Background:
- Microsurgical clipping is the standard durable treatment for cerebral aneurysms.
- Aneurysm recurrence post-clipping is rare but carries a high risk of rupture.
- Reoperation for recurrent aneurysms is complex due to scar tissue and adhesions.
Observation:
- This study retrospectively analyzed seven patients who received Pipeline Embolization Device (PED) placement for recurrent aneurysms after prior clipping.
- The median time from initial clipping to recurrence diagnosis was 13 years.
- No morbidity or mortality was observed during or after PED placement.
Findings:
- Pipeline Embolization Device (PED) placement resulted in complete aneurysm occlusion in all patients.
- Previous microsurgical clipping did not negatively impact PED placement or treatment outcomes.
- This represents a rare but important report on PED for recurrent aneurysms.
Implications:
- Pipeline Embolization Device (PED) placement may be a viable and safe alternative to repeat surgical clipping for recurrent cerebral aneurysms.
- This treatment option could potentially reduce the risks associated with reoperation in challenging cases.
- Further research is warranted to establish PED as a standard treatment for this specific indication.
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