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Related Experiment Videos

[Determination of the right ventricular ejection fraction from the exponential decrease in the thermodilution

R Unterberg1, H P Gruber, O Ickrath

  • 1Medizinische Klinik, Universität Tübingen.

Zeitschrift Fur Kardiologie
|May 1, 1989
PubMed
Summary

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Thermodilution accurately estimates right ventricular ejection fraction in normal hearts but is unreliable for dilated ventricles. This method

Area of Science:

  • Cardiology
  • Medical Imaging
  • Hemodynamics

Background:

  • Right ventricular ejection fraction (RVEF) is a crucial hemodynamic parameter.
  • Thermodilution curves offer a method for calculating RVEF and volumes.
  • Clinical validation of thermodilution for RVEF assessment is necessary.

Purpose of the Study:

  • To evaluate the accuracy of thermodilution for RVEF and volume measurements.
  • To compare thermodilution results with biplane cineventriculography.
  • To determine the clinical applicability of thermodilution in various patient groups.

Main Methods:

  • Thermodilution curves were analyzed using exponential downslope.
  • Right ventricular ejection fraction and volumes were calculated via thermodilution.

Related Experiment Videos

  • Measurements were compared to biplane cineventriculography in 40 patients.

    • Main Results:

    • Thermodilution showed good correlation for RVEF in patients with normal end-diastolic volumes (r=0.82).
    • Significant discrepancies (up to 25%) were observed in patients with low or high end-diastolic volumes.
    • Volume measurements demonstrated lower correlations and higher variability compared to angiography.

    Conclusions:

    • Thermodilution provides an approximate RVEF assessment primarily in patients with normal right ventricles.
    • The method's accuracy is limited in cases of right ventricular dilatation.
    • Clinical use of thermodilution for RVEF is restricted, especially in dilated cardiomyopathy.