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Related Concept Videos

Drug Dosage Regimen: Overview01:15

Drug Dosage Regimen: Overview

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A drug dosage regimen describes the specific instructions and schedule for administering a drug to a patient. It considers factors such as drug dosage, frequency, route of administration, and duration of treatment. Designing an appropriate dosage regimen for a patient aims to achieve a target drug concentration at the site of action.
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Dosage Regimen: Individualization01:24

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Individualization in dosing regimens is the customization of medication doses for individual patients. Its necessity arises from the goal of maximizing therapeutic benefits while minimizing risks. This approach is pivotal because human responses to drugs can vary widely; what is effective for one person may be inadequate or excessive for another. Interpatient (intersubject) variability refers to differences in drug responses between individuals, while intrapatient (intrasubject) variability...
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Drug Administration and Therapy Phases: Overview01:26

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Drugs, the chemical agents used in diagnosing, treating, or preventing diseases, undergo a four-phase process of development: pharmaceutic, pharmacokinetics, pharmacodynamics, and therapeutic.
The pharmaceutical phase focuses on leveraging the physicochemical properties of the drug to design and manufacture an effective product. Variants include orally administered tablets or capsules, topical creams or ointments, and parenteral-delivery solutions or emulsions.
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Antihypertensive Drugs: Thiazide-Class Diuretics01:15

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Thiazide diuretics are sulfonamide derivatives featuring a benzothiadiazine ring system in their molecular structure. Based on this structure, thiazide diuretics can be categorized into two groups: thiazide-type and thiazide-like diuretics. Thiazide-type diuretics, including hydrochlorothiazide and chlorothiazide, consist of a benzothiadiazine backbone with an attached sulfonamide group. Thiazide-like diuretics, such as chlorthalidone and indapamide, lack the thiazide ring but demonstrate...
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Drug Biotransformation: Overview01:16

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Pharmaceutical substances known as xenobiotics are predominantly lipophilic and nonionized. This enables them to permeate lipid bilayers, such as cell membranes, and interact with intracellular target receptors. Lipophilic drugs have an advantage in crossing biological barriers and reaching their intended sites of action. However, lipophilic drugs often have a restricted capacity for renal expulsion or elimination from the body. When these drugs enter the kidneys and undergo glomerular...
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Drug Biotransformation: Overview01:28

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Biotransformation, also known as drug metabolism, is a vital physiological process that chemically alters drugs, facilitating their elimination from the body and terminating their action. This process involves two main phases: phase I and phase II reactions. Phase I reactions, including oxidation, reduction, and hydrolysis, introduce or unmask polar functional groups on the drug molecule, thereby increasing its water solubility. By enhancing water solubility, the drug becomes more hydrophilic...
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Multiplex Therapeutic Drug Monitoring by Isotope-dilution HPLC-MS/MS of Antibiotics in Critical Illnesses
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Drug information.

Ruth Williams

    Nursing Management (Harrow, London, England : 1994)
    |June 29, 2016
    PubMed
    Summary
    This summary is machine-generated.

    Pharmapedia, a new pharmacy information platform, has been developed. This resource aims to enhance pharmaceutical knowledge sharing and accessibility for professionals.

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    Area of Science:

    • Pharmacy Practice
    • Information Science

    Background:

    • Limited access to centralized, reliable pharmacy information can hinder clinical decision-making.
    • The need for a comprehensive digital resource for pharmaceutical data is recognized.

    Purpose of the Study:

    • To introduce Pharmapedia, a novel pharmacy information platform.
    • To provide a centralized hub for pharmaceutical knowledge and resources.

    Main Methods:

    • Development of a digital platform by the UK Clinical Pharmacy Association.
    • Collaboration with partner organizations to aggregate and structure information.

    Main Results:

    • Pharmapedia has been successfully developed and launched.
    • The platform serves as a key resource for pharmacy professionals.

    Conclusions:

    • Pharmapedia represents a significant advancement in pharmacy information accessibility.
    • The platform is expected to support evidence-based practice and professional development.