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Clinical application of extracorporeal membrane oxygenation in children with refractory cardiopulmonary failure

Zi-Hao Yang1, Bo-Tao Ning2, Chen-Mei Zhang1

  • 1Department of PICU, Children's Hospital, Zhejiang University School of Medicine, Hangzhou, China.

World Journal of Pediatrics : WJP
|June 29, 2016
PubMed

Insights

Extracorporeal membrane oxygenation (ECMO) effectively supports children with severe cardiopulmonary failure. This therapy, particularly for acute fulminant myocarditis, shows a 58.3% survival rate in pediatric patients.

Area of Science:

  • Pediatric Critical Care Medicine
  • Cardiovascular Surgery
  • Respiratory Support

Background:

  • Refractory cardiopulmonary failure presents a critical challenge in pediatric intensive care.
  • Extracorporeal membrane oxygenation (ECMO) offers a life-saving intervention for severe cases.

Purpose of the Study:

  • To describe the clinical experience of utilizing ECMO in pediatric patients with refractory cardiopulmonary failure.
  • To evaluate the efficacy and outcomes of ECMO support in this vulnerable population.

Main Methods:

  • Retrospective review of 12 pediatric patients treated with ECMO.
  • Data collected from February 2009 to August 2015 in a Pediatric Intensive Care Unit (PICU).

Main Results:

  • A survival rate of 58.3% (7/12) was achieved, with successful weaning from ECMO.
  • Five patients presented with acute fulminant myocarditis (AFM), a key indication.
  • Complications included hemorrhage, hemolysis, thrombosis, acute kidney injury, and infection.

Conclusions:

  • ECMO is a valuable therapeutic option for children with refractory cardiopulmonary failure.
  • ECMO demonstrates particular utility in the management of acute fulminant myocarditis in pediatric patients.
Abstract

Keywords:
acute fulminant myocarditisacute respiratory distress syndromeextracorporeal membrane oxygenation

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