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Regulation of SET Gene Expression by NFkB

Yi Feng1, Xiaoyong Li1, Weitao Zhou1

  • 1Chongqing City Key Lab of Translational Medical Research in Cognitive Development and Learning and Memory Disorders and Ministry of Education Key Lab of Child Development and Disorders, Children's Hospital of Chongqing Medical University, Chongqing, 400014, China.

Molecular Neurobiology
|June 29, 2016
PubMed
Summary

Nuclear factor kappa B (NFkB) regulates the SET gene, which is implicated in Alzheimer's disease (AD) and Down syndrome (DS) tau pathology. This finding sheds light on how inflammatory responses may contribute to AD pathogenesis.

Keywords:
Alzheimer’s diseaseNFkBSETSp1Transcription

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