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Development and Validation of an Oral Anticoagulation Knowledge Tool (AKT)
Kehinde O Obamiro1, Leanne Chalmers1, Luke R E Bereznicki1
1Pharmacy, School of Medicine, University of Tasmania, Hobart, Australia.
Plos One
|June 29, 2016
Summary
A new Anticoagulation Knowledge Tool was developed and validated for all oral anticoagulants. This reliable instrument assesses patient understanding, improving anticoagulation therapy outcomes in clinical practice.
Area of Science:
- Pharmacology
- Medical Education
- Health Outcomes
Background:
- Assessing patient knowledge of anticoagulation is crucial for effective treatment and improved outcomes.
- Existing tools are primarily for warfarin and not suitable for direct-acting oral anticoagulants (DOACs).
Purpose of the Study:
- To develop and validate a comprehensive oral anticoagulation knowledge instrument.
- The tool aims to be applicable across all types of oral anticoagulant medications.
Main Methods:
- Ten anticoagulation experts contributed to content validity.
- The Anticoagulation Knowledge Tool was administered to 44 pharmacists, 50 patients, and 50 general public members.
- Reliability was assessed via test-retest on subgroups, with statistical analysis for validity and item performance.
Main Results:
- The 28-item instrument demonstrated strong content validity (index 0.92).
- Significant differences in scores across groups (pharmacists > patients > public) supported construct validity.
- Acceptable internal consistency (Cronbach's α > 0.7) and good test-retest reliability (r=0.72-0.78) were confirmed.
Conclusions:
- The Anticoagulation Knowledge Tool is a valid and reliable measure of anticoagulation knowledge.
- It is suitable for routine clinical use to assess patient understanding of oral anticoagulants.
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