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Updated: Mar 18, 2026

X-Ray Crystallography to Study the Oligomeric State Transition of the Thermotoga maritima M42 Aminopeptidase TmPep1050
Published on: May 13, 2020
Anion recognition by oligo-(thio)urea-based receptors
Chuandong Jia1, Wei Zuo1, Dan Zhang1
1Key Laboratory of Synthetic and Natural Functional Molecule Chemistry of the Ministry of Education, College of Chemistry and Materials Science, Northwest University, Xi'an 710069, China. wubiao@nwu.edu.cn.
Oligo-ureas and oligo-thiourreas are effective anion receptors. Recent advances focus on their construction and anion binding, particularly ortho-phenylene-connected structures for supramolecular assembly.
Area of Science:
- Supramolecular Chemistry
- Organic Chemistry
- Coordination Chemistry
Background:
- Oligo-(thio)ureas are versatile receptors for anion recognition.
- Their structural diversity enables tailored anion binding properties.
Purpose of the Study:
- To review recent progress in oligourea synthesis and anion coordination chemistry.
- To highlight geometric factors crucial for effective anion binding.
- To discuss applications in supramolecular self-assembly.
Main Methods:
- Summarizing metal-coordination assisted and covalently linked oligourea receptors.
- Analyzing geometric characteristics for anion complementarity.
- Focusing on ortho-phenylene-connected systems.
Main Results:
- Oligo-(thio)ureas exhibit significant potential in anion recognition.
- Specific geometric arrangements are key for selective anion binding.
- Ortho-phenylene-connected oligoureas facilitate the self-assembly of complex architectures like helicates and cages.
Conclusions:
- Oligo-(thio)ureas are a valuable class of anion receptors.
- Understanding structure-property relationships is vital for designing advanced receptors.
- These compounds are instrumental in constructing sophisticated supramolecular structures.
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