Related Experiment Video
Updated: Mar 18, 2026

In Vitro Method to Control Concentrations of Halogenated Gases in Cultured Alveolar Epithelial Cells
Published on: October 23, 2018
The Optimum Level of Sevoflurane in Pediatric Echocardiography
Fan Conghai1, Zhang Fengchao2, Shan Chengjing1
1Xuzhou Children's Hospital, Xuzhou, 221006, China.
Abstract:
Sevoflurane is shown to be safe and effective in pediatric echocardiography. This study explores the optimum level in pediatric echocardiography. One hundred and twenty children, with an age range of 35 days-3 years, were included in this study. The children with severe cyanotic congenital heart disease or severe pneumonia, which was Grade I or II according to the American College of Physicians Guideline Grading, were excluded. All children received the anesthesia with sevoflurane. The inhalation anesthesia level decreased from 2.5 to 1.0 %, with a decrement of 0.5 %. The induction time (T0), echocardiography time (T1), and time to awakening (T2) in each child were recorded, and the changes in the blood pressure, heart rate, breath, and oxygen saturation in each child were also monitored. The Ramsay scale scoring during anesthesia and the case number of failure in echocardiography in each group were also recorded. When the level of sevoflurane inhalation was maintained at 1.0 %, the childrens' scores were low, including 8 incompliant children, and p < 0.05 in comparison with other groups. The scores increased as the sevoflurane inhalation level increased. When the sevoflurane inhalation increased to 1.5 %, the children could sleep with stable blood pressure, and no dysphoria occurred during the echocardiography. When the sevoflurane inhalation level increased to 2.5 %, the Ramsay scores did not increase. However, the T2 significantly increased (p < 0.05). The blood pressure and heart rate in each group did not change significantly. With the premise of safety and efficacy in children, the optimum level of sevoflurane in pediatric echocardiography was 1.5-2.0 %.
More Related Videos
07:55Echocardiographic Characterization of Left Ventricular Structure, Function, and Coronary Flow in Neonate Mice
Published on: April 7, 2022
03:02Application of Dixon's Up-and-Down Design to Estimate the Minimum Alveolar Concentration of Sevoflurane in Rats with Refined Movement Classification
Published on: July 25, 2025
Related Concept Videos
Imaging Studies for Cardiovascular System II:Types of Echocardiography
Types of Echocardiography
Transthoracic Echocardiography (TTE)
TTE is the most common type of echocardiogram which involves placing a transducer on the patient's chest, emitting sound waves to create heart images. TTE is invaluable for evaluating the heart's size, structure, and motion, making it particularly useful for...
Imaging Studies for Cardiovascular System I:Echocardiography
Indications: Echocardiography is utilized to diagnose heart failure, valve disorders, and myocardial infarction. It also assesses cardiac structures' size, shape, and motion,...
Assessment of Diffusion and Perfusion
The Role of Diffusion in Respiration
Diffusion is the process by which molecules move from an area of higher concentration to an area of lower concentration. In the respiratory system, this...