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Symptomatic Diverticulosis Is Characterized By Loose Stools.

M Ellionore Järbrink-Sehgal1, Anna Andreasson2, Nicholas J Talley3

  • 1Department of Medicine Solna, Karolinska Institutet, Center for Digestive Diseases, Karolinska University Hospital, Stockholm, Sweden; Department of Gastroenterology, Baylor College of Medicine, Houston, Texas.

Clinical Gastroenterology and Hepatology : the Official Clinical Practice Journal of the American Gastroenterological Association
|June 30, 2016
PubMed
Summary

Diverticulosis prevalence increases with age and is linked to diarrhea across all ages. In individuals over 60, diverticulosis is also associated with abdominal pain and irritable bowel syndrome (IBS).

Keywords:
ColonoscopyDiverticulosisIrritable Bowel Syndrome (IBS)Population-BasedSymptomatic Uncomplicated Diverticular Disease (SUDD)

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Area of Science:

  • Gastroenterology
  • Epidemiology
  • Clinical Medicine

Background:

  • Symptomatic uncomplicated diverticular disease is distinct from irritable bowel syndrome (IBS).
  • Population-based data on diverticulosis prevalence and associations are limited.
  • Diverticulosis may be linked to colonic symptoms and mental health.

Purpose of the Study:

  • To investigate the prevalence and location of diverticulosis in the general population.
  • To examine the association between diverticulosis and colonic symptoms.
  • To explore the relationship between diverticulosis and mental health.

Main Methods:

  • A population-based study of 742 randomly selected adults (aged 18-70) in Sweden.
  • Participants underwent colonoscopy and completed validated symptom and mental health questionnaires.
  • Logistic regression analyzed associations between diverticulosis, demographics, symptoms, and mental health.

Main Results:

  • Diverticulosis was present in 17.5% of participants, increasing significantly with age.
  • Sigmoid involvement was universal in those with diverticulosis.
  • Diverticulosis correlated with loose stools, urgency, mucus, and high stool frequency.
  • In participants over 60, diverticulosis was linked to abdominal pain and diarrhea-predominant IBS.

Conclusions:

  • Diverticulosis prevalence is strongly age-dependent.
  • Diverticulosis is associated with diarrhea in all age groups.
  • In older adults, diverticulosis is linked to abdominal pain and diarrhea-predominant IBS.