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Published on: July 21, 2023
Innominate Artery Stenosis Presenting With Migratory Digital Ischemia
Yen-Yi Juo1, Lisbi Rivas Ramirez2, Garry Ruben2
1Department of Surgery, George Washington University Medical Center, Washington, DC, USA yjuo@gwu.edu.
Insights
Migratory digital ischemia can signal rare atherosclerotic disease in major arteries. A combined open and endovascular approach, using carotid control, safely treated innominate artery stenosis and prevented stroke.
Area of Science:
- Vascular Surgery
- Interventional Cardiology
- Neurology
Background:
- Supra-aortic vessel atherosclerosis can cause embolic events or low flow.
- Endovascular treatment of these lesions carries stroke risk due to plaque manipulation.
- Combined operative-endovascular approaches may mitigate intraoperative stroke risk.
Observation:
- An 84-year-old female presented with migratory digital cyanosis progressing to gangrene.
- Angiography revealed severe atherosclerotic plaque and proximal innominate artery stenosis.
- A novel approach involved carotid artery control before retrograde balloon-stent angioplasty.
Findings:
- The combined endovascular-operative intervention was technically successful.
- The patient experienced an uneventful recovery with no new neurological deficits.
- Digital ischemia resolved, with no progression at 2-week follow-up.
Implications:
- Migratory digital ischemia is an uncommon but significant manifestation of supra-aortic atherosclerosis.
- Retrograde angioplasty with distal carotid control offers a safe and effective option for selected patients.
- This approach minimizes embolic risk during endovascular intervention for complex aortic arch lesions.
Background:
Atherosclerotic lesions of the supra-aortic trunk vessels, including the innominate artery, subclavian artery, or the common carotid artery, tend to present either as low-flow state distal to the lesion or as embolic events. The risk of embolic cerebrovascular event complicates the management of this condition via a pure endovascular approach. A combined operative-endovascular intervention may be a valuable approach in order to reduce the risk of intraoperative stroke and prevent future embolic events.
Case Presentation:
An 84-year-old female presented at the emergency department (ED) with a 4-month history of migratory digital cyanotic lesions across various fingers on her right hand. The lesion eventually progressed into dry gangrene on her right middle finger. Selective angiography of the aortic arch vessels demonstrated significant atherosclerotic plaque burden throughout her supra-aortic vessels and a segmental stenosis at the proximal innominate artery. A right carotid cut down was performed to allow clamping of the carotid artery so as to minimize the risk of intraoperative stroke from plaque manipulation. Retrograde balloon angioplasty was performed, and stent was placed across the stenotic segment. The patient tolerated the procedure well and had an uneventful postoperative course. She was discharged on postoperative day 3. At 2-week follow-up, she has had no progression of her digital ischemia nor other focal cranial nerve deficits.
Conclusion:
Migratory digital ischemia is a rare presentation of atherosclerotic disease of the supra-aortic vessels. It represents a challenging situation for endovascular intervention due to concern about plaque dislodgment during the procedure. A retrograde balloon-stent angioplasty following distal carotid control with an open approach may be safe and effective in selected patients.
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