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Updated: Mar 18, 2026

Generating Acute and Chronic Experimental Models of Motor Tic Expression in Rats
Published on: May 27, 2021
Severe Neurological Complications Associated With Tourette Syndrome
Amy L Patterson1, Asim F Choudhri1, Masanori Igarashi1
1Division of Neurology, Department of Pediatrics, University of Tennessee Health Science Center, Memphis, Tennessee; Division of Neurology, Department of Pediatrics, Le Bonheur Children's Hospital, Memphis, Tennessee.
Background:
Tics and Tourette syndrome are common problems evaluated by both the general pediatrician and pediatric neurologist. The common comorbidities of tics are well known, but the severe neurological complications are rare and may not be appreciated.
Methods:
This is a retrospective case series and literature review.
Results:
We present here four adolescents with Tourette syndrome who had severe neurological complications secondary to motor tics. We provide the history, neurological examination, and radiological findings in addition to a review of previously reported cases of vascular and cervical cord complications associated with violent motor tics.
Conclusions:
We highlight the importance of recognizing the presenting signs of these complications early and the need to vigorously treat violent motor tics to prevent significant neurological complications.
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