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Cochlear dialysis for Menière's disease. An update
1Department of Otolaryngology, London Hospital, England.
The American Journal of Otology
|March 1, 1989
Summary
Hyperosmolar perfusion of the scala tympani using mannitol and dextrose effectively reduced Meniere's disease symptoms in early trials. This cochlear dialysis technique offers a potential treatment for endolymphatic hydrops.
Area of Science:
- Otolaryngology
- Neurosurgery
- Medical Devices
Background:
- Meniere's disease is characterized by endolymphatic hydrops.
- Previous treatments included "salt in the round window niche" since 1972.
Purpose of the Study:
- To report early results of hyperosmolar perfusion for advanced Meniere's disease.
- To evaluate the efficacy of cochlear dialysis.
Main Methods:
- Thirty patients with advanced Meniere's disease were treated between March 1981 and March 1986.
- Hyperosmolar perfusion of the scala tympani with a sterile solution of mannitol in 5% dextrose (350 m.osm/L) was administered.
- Follow-up ranged from 2 to 7 years.
Main Results:
- Early results indicated a reduction in endolymphatic hydrops.
- The technique demonstrated potential for managing Meniere's disease symptoms.
Conclusions:
- Hyperosmolar perfusion of the scala tympani is a viable extension of previous treatments.
- Cochlear dialysis shows promise for advanced Meniere's disease.
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