Related Experiment Video

Updated: Mar 18, 2026

Isolation of Neonatal Extrahepatic Cholangiocytes
07:54

Isolation of Neonatal Extrahepatic Cholangiocytes

Published on: June 5, 2014

10.9K

Neonatal jaundice

Erin Dean

    Nursing Standard (Royal College of Nursing (Great Britain) : 1987)
    |June 30, 2016
    PubMed

    Insights

    Jaundice is a common condition in newborns caused by high bilirubin levels. While usually harmless, prompt identification of potentially harmful high bilirubin levels is crucial.

    Area of Science:

    • Neonatal Medicine
    • Pediatrics
    • Clinical Biochemistry

    Background:

    • Jaundice is a frequent condition in newborns, affecting approximately 60% of infants.
    • Premature infants exhibit higher incidences of jaundice.
    • The condition arises from elevated bilirubin levels in the blood.

    Purpose of the Study:

    • To outline the essential facts regarding neonatal jaundice.
    • To emphasize the importance of monitoring bilirubin levels in newborns.

    Main Methods:

    • This summary is based on established clinical knowledge and epidemiological data regarding neonatal jaundice.
    • Information is synthesized from pediatric and neonatal medical literature.

    Main Results:

    • Neonatal jaundice is characterized by increased blood bilirubin.
    • Most cases are benign and resolve spontaneously within two weeks.
    • A subset of cases involves dangerously high bilirubin levels requiring medical intervention.

    Conclusions:

    • Early detection and management of neonatal jaundice are vital.
    • Prompt identification of elevated bilirubin levels is necessary to prevent potential harm.

    More Related Videos

    Biochemical Measurement of Neonatal Hypoxia13:13

    Biochemical Measurement of Neonatal Hypoxia

    Published on: August 24, 2011

    14.5K
    How to Administer Near-Infrared Spectroscopy in Critically ill Neonates, Infants, and Children07:27

    How to Administer Near-Infrared Spectroscopy in Critically ill Neonates, Infants, and Children

    Published on: August 19, 2020

    12.8K

    Related Concept Videos

    Changes in Skin Color: Clinical Perspectives01:14

    Changes in Skin Color: Clinical Perspectives

    The first thing a clinician sees is the skin, so the examination of the skin should be part of any thorough physical examination. Most skin disorders are relatively benign, but a few, including melanomas, can be fatal if untreated. A couple of the more noticeable disorders, albinism and vitiligo, affect the appearance of the skin and its accessory organs.
    Albinism
    Albinism is a genetic disorder that affects (completely or partially) the coloring of skin, hair, and eyes. The defect is primarily...
    4.1K
    Diseases of the Liver and Gallbladder01:26

    Diseases of the Liver and Gallbladder

    Liver and gallbladder diseases are a significant health concern, with prominent conditions including cirrhosis, hepatitis, non-alcoholic fatty liver disease (NAFLD), and gallstones. Jaundice is a common manifestation of liver and biliary disease.
    Cirrhosis is characterized by the scarring of hepatic lobules in the liver, which are replaced by fibrous tissue, affecting the liver's normal functioning. NAFLD, on the other hand, is caused by an excessive build-up of fat in the liver, not...
    2.2K
    Pharmacokinetics in Pediatric Patients: Drug Metabolism01:24

    Pharmacokinetics in Pediatric Patients: Drug Metabolism

    In pediatric care, understanding the nuances of hepatic drug metabolism is crucial, as it significantly differs from that of adults. This divergence is primarily due to the developmental stage of drug-metabolizing enzymes, which affects how medications are processed in the body. In neonates, for instance, the activity of Phase I enzymes—critical for the initial breakdown of drugs—is markedly reduced, functioning at just 20–40% of the levels seen in adults. This reduction poses...
    313
    Inborn Errors of Metabolism01:20

    Inborn Errors of Metabolism

    Phenylketonuria (PKU) is a protein metabolism disorder characterized by high blood levels of the amino acid phenylalanine. This results from a mutation in the gene responsible for phenylalanine hydroxylase, an enzyme that converts phenylalanine into tyrosine. When this enzyme is deficient, phenylalanine builds up in the blood, leading to symptoms such as vomiting, rashes, seizures, growth deficiency, and severe mental retardation. An early diagnosis and a diet restricting phenylalanine intake...
    990
    Pigmentation01:19

    Pigmentation

    The color of the skin is influenced by a number of pigments, including melanin, carotene, and hemoglobin. Recall that melanin is produced by cells called melanocytes, which are found scattered throughout the stratum basale of the epidermis. The melanin is transferred to the keratinocytes via melanosomes.
    Melanin occurs in two primary forms: eumelanin that provides black and brown pigment and pheomelanin that provides red color. Dark-skinned individuals produce more melanin than those with pale...
    4.9K
    Pharmacokinetics in Pediatric Patients: Overview and Drug Absorption01:23

    Pharmacokinetics in Pediatric Patients: Overview and Drug Absorption

    Understanding the physiological differences in the pediatric population is crucial for effective pharmacotherapy. Neonates, infants, and children exhibit significant variations in gastric pH, gastric emptying time, intestinal transit time, and biliary function. These variations profoundly affect oral drug absorption, necessitating a nuanced approach to pediatric dosing.Neonates present with a unique physiological profile, having a gastric pH greater than 4 and faster and more irregular gastric...
    647