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Updated: Mar 18, 2026

Determining Immune System Suppression versus CNS Protection for Pharmacological Interventions in Autoimmune Demyelination
Published on: September 12, 2016
Disease Modifying Therapy in Multiple Sclerosis
U E Williams1, S K Oparah1, E E Philip-Ephraim1
1Internal Medicine Department, University of Calabar, Calabar 540242, Cross River State, Nigeria.
Abstract:
Multiple sclerosis is an autoimmune disease of the central nervous system characterized by inflammatory demyelination and axonal degeneration. It is the commonest cause of permanent disability in young adults. Environmental and genetic factors have been suggested in its etiology. Currently available disease modifying drugs are only effective in controlling inflammation but not prevention of neurodegeneration or accumulation of disability. Search for an effective neuroprotective therapy is at the forefront of multiple sclerosis research.
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