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Published on: February 23, 2020
[Study on acute inhalation toxicity of Luowei, a plant molluscacide]
Objective:
To study the acute inhalation toxicity of 50% Luowei, a plant molluscacide, in rats.
Methods:
Twenty adult Wistar rats, half male and half female, were given of 5000 mg/m³ of 50% Luowei through a dynamic inhalation device and the death and recovery of the rats were observed within 14 days, and LC₅₀ was drawn.
Results:
After exposure, the activities of the rats decreased and a few individual animals had scratching symptom, but the symptom disappeared after the exposure. No animals died during the whole observation period. Therefore, the acute inhalation LC₅₀ was greater than 5000 mg/m³ for rats, and Luowei belonged to low toxicity level.
Conclusions:
50% Luowei will not cause animal death if it is inhaled into animal body. However, people still need to wear protective equipment in production and use.
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