Related Experiment Video

Updated: Mar 18, 2026

Dual Effects of Melanoma Cell-derived Factors on Bone Marrow Adipocytes Differentiation
07:00

Dual Effects of Melanoma Cell-derived Factors on Bone Marrow Adipocytes Differentiation

Published on: August 23, 2018

6.6K

Steroid changes adipokine concentration in the blood and bone marrow fluid

Tatsuya Fukushima, Akira Hozumi, Masato Tomita

    Biomedical Research (Tokyo, Japan)
    |July 1, 2016
    PubMed

    More Related Videos

    Mechanism of Regulation of Adipocyte Numbers in Adult Organisms Through Differentiation and Apoptosis Homeostasis08:34

    Mechanism of Regulation of Adipocyte Numbers in Adult Organisms Through Differentiation and Apoptosis Homeostasis

    Published on: June 3, 2016

    15.9K
    Osteoclast Derivation from Mouse Bone Marrow06:17

    Osteoclast Derivation from Mouse Bone Marrow

    Published on: November 6, 2014

    25.1K

    Related Concept Videos

    Hormones of the Adrenal Glands01:31

    Hormones of the Adrenal Glands

    Adrenal hormones play a pivotal role in maintaining the body's electrolyte balance and orchestrating responses to stress, showcasing the intricate functions of the adrenal cortex and medulla.
    The adrenal cortex, a powerhouse of hormone synthesis, generates over two dozen corticosteroid hormones. The zona glomerulosa produces mineralocorticoids, exemplified by aldosterone, influencing the electrolyte composition of body fluids. The synthesis of glucocorticoids such as cortisol and...
    6.3K
    Bone Disorders01:29

    Bone Disorders

    Aging and its effect on bone remodeling is the most common cause of bone disorders. In young and healthy people, bone deposition and resorption happen at an equal rate to maintain optimal bone health.
    Bone deposition is also affected by the levels of sex hormones like estrogen and testosterone that promote osteoblast activity and bone matrix synthesis. When the level of these hormones decreases due to aging, it causes a reduction in bone deposition. As a result, bone resorption by osteoclasts...
    6.3K
    Hormones and Bone Tissue01:17

    Hormones and Bone Tissue

    The endocrine system produces and secretes hormones, which interact with the skeletal system. These hormones control bone growth, maintain bone once it is formed, and remodel it.
    Hormones That Influence Osteoblasts and/or Maintain the Matrix
    Several hormones are necessary for controlling bone growth and maintaining the bone matrix. The pituitary gland secretes growth hormone (GH), which, as its name implies, controls bone growth. This happens in several ways: first, it triggers chondrocyte...
    4.2K
    Osteoclasts in Bone Remodeling01:31

    Osteoclasts in Bone Remodeling

    Osteoclasts are cells responsible for bone resorption and remodeling. They originate from hematopoietic progenitor cells present in the bone marrow. Numerous progenitor cells fuse to form multinucleated cells, each with 10-20 nuclei. A single osteoclast has a diameter of 150 to 200 µM. These cells have ruffled borders that break down the underlying bone tissue and release minerals such as calcium into the blood in bone resorption. Osteoclasts cling to bones with their ruffled edges during...
    4.6K
    Bone Remodeling01:40

    Bone Remodeling

    Bone remodeling is a continuous and balanced process of bone resorption by osteoclasts and bone formation by osteoblasts. In adults, it helps maintain bone mass and calcium homeostasis. While mechanical stress can stimulate turnover as part of the normal maintenance and reparative process, several hormones also regulate bone remodeling.
    40.9K
    Target Cell Response to Hormones01:22

    Target Cell Response to Hormones

    Hormones intricately bind to receptors on the surface or within target cells, initiating a cascade of cellular responses.
    Notably, the cellular response can be regulated by altering the number of receptors expressed in the cell. For example, prolonged exposure to elevated hormone levels results in a gradual decline or down-regulation in the number of receptors for that specific hormone on the cell surface. Conversely, in response to low hormone levels, cells may use up-regulation, producing an...
    6.1K