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Precision medicine in cardiology

Elliott M Antman1, Joseph Loscalzo2

  • 1Brigham and Women's Hospital, TIMI Study Group, 350 Longwood Avenue, Office Level One, Boston, Massachusetts 02115, USA.

Nature Reviews. Cardiology
|July 1, 2016
PubMed

Insights

Precision medicine offers a new era for cardiovascular research, integrating diverse data to improve individual and population health. This approach empowers patients as active participants in their care, moving beyond traditional disease silos.

Area of Science:

  • Cardiovascular Medicine
  • Genomics
  • Public Health

Background:

  • Noncommunicable diseases are a leading cause of death globally.
  • Current medical approaches often remain siloed, limiting comprehensive understanding of disease.
  • Precision medicine offers a transformative framework for cardiovascular health.

Purpose of the Study:

  • To outline the potential of precision medicine in cardiovascular research and clinical practice.
  • To identify necessary tools and data types for implementing precision cardiovascular medicine.
  • To address challenges and propose a future vision for integrated cardiovascular healthcare.

Main Methods:

  • Integration of multi-omic data, exposome, social determinants, microbiome, behavioral data, and electronic health records.
  • Leveraging existing cardiovascular expertise to drive discovery science and clinical research efficiency.
  • Addressing technical and sociopolitical barriers to precision medicine implementation.

Main Results:

  • Precision medicine requires novel tools to characterize individual and population cardiovascular health.
  • Cardiovascular specialists can enhance research and clinical efficiency through precision approaches.
  • Implementation necessitates overcoming technical and sociopolitical hurdles.

Conclusions:

  • Precision medicine can revolutionize cardiovascular health by providing more accurate insights for individuals and populations.
  • Active patient participation and shared decision-making are central to the precision healthcare model.
  • Moving beyond siloed medicine towards a universal precision medicine environment is essential for future health advancements.

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