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Functional Photoacoustic Imaging of Gastric Acid Secretion Using pH-Responsive Polyaniline Nanoprobes
Junwei Li1, Hong Xiao2, Soon Joon Yoon1
1Department of Bioengineering, University of Washington, Seattle, WA, 98195, USA.
Small (Weinheim an Der Bergstrasse, Germany)
|July 1, 2016
Abstract:
A stomach functional imaging technique based on photoacoustics achieves noninvasive gastric acid secretory assessment utilizing pH-responsive polyaniline nanoprobes. A testing protocol mimicking clinical practice is established using a mouse model. After imaging, the nanoprobes are excreted outside the body without inducing systematic toxicity. Further optimization and translation of this technology can help alleviate patients' suffering and side effects.
