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Updated: Mar 18, 2026

Targeted Next-generation Sequencing and Bioinformatics Pipeline to Evaluate Genetic Determinants of Constitutional Disease
Published on: April 4, 2018
Electronic health record interventions at the point of care improve documentation of care processes and decrease
Maren T Scheuner1,2, Jane Peredo1, Kelly Tangney1
1VA Greater Los Angeles Healthcare System, Los Angeles, California, USA.
Electronic health record (EHR) tools significantly improved documentation for genetic testing processes. These tools also led to a decrease in genetic tests ordered by non-geneticists, enhancing care quality.
Area of Science:
- Medical Informatics
- Clinical Genetics
- Health Services Research
Background:
- Genetic testing is increasingly utilized, necessitating robust documentation of care processes.
- Nongeneticists often order genetic tests, highlighting the need for improved clinical support and documentation tools.
Purpose of the Study:
- To evaluate the impact of electronic health record (EHR) point-of-care tools on the documentation of pre- and postanalytic care for genetic tests.
- To assess whether EHR tools influence the utilization patterns of genetic tests ordered by non-specialists.
Main Methods:
- A nonrandomized, controlled, pre-/postintervention study design was employed.
- EHR point-of-care tools, including informational messages and a template report, were implemented for three genetic tests.
- Chart review and statistical analyses (linear and logistic regressions) were used to assess documentation quality and utilization rates.
Main Results:
- The intervention site showed significant improvements in mean documentation scores and the proportion of records with clinically meaningful documentation compared to the control site.
- Documentation scores were positively associated with abnormal test results and trainee providers, and postimplementation, with the intervention site and specialty clinics.
- A significant decrease in the utilization of genetic tests was observed at the intervention site postimplementation, but not at the control site.
Conclusions:
- EHR point-of-care tools effectively enhance the documentation of genetic testing processes.
- Implementation of EHR tools can lead to a reduction in the utilization of genetic tests ordered by nongeneticists, suggesting improved appropriateness of testing.
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