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Pacific Island Pharmacovigilance: The Need for a Different Approach
John McEwen1, Lasse S Vestergaard2,3,4, Amanda L C Sanburg5
1, 253 La Perouse Street, Red Hill, ACT, 2603, Australia. mcewenj@webone.com.au.
Drug Safety
|July 2, 2016
Summary
Pacific Island countries need a tailored approach to pharmacovigilance (PV) due to limited resources. Focusing initially on reporting medicine problems, like substandard and counterfeit drugs, is a practical strategy.
Area of Science:
- Global Health
- Pharmaceutical Sciences
- Public Health Policy
Background:
- Pacific Island countries (PICs) receive Global Fund support for major diseases.
- Existing pharmacovigilance (PV) systems in PICs often fall short of Global Fund and WHO standards.
- Limited health system resources pose significant challenges to establishing robust PV.
Purpose of the Study:
- To propose a pragmatic approach for advancing pharmacovigilance in resource-limited settings like PICs.
- To advocate for a focused strategy on critical aspects of PV, such as detecting medicine quality issues.
- To explore sustainable models for PV support within existing aid structures.
Main Methods:
- Conceptual analysis and strategic proposal development.
- Review of existing pharmacovigilance frameworks and resource limitations in PICs.
- Identification of priority areas for PV system strengthening.
Main Results:
- A phased approach to PV development is recommended, prioritizing the reporting of substandard and counterfeit medicines.
- Integration of PV support within existing medicine supply aid mechanisms is suggested.
- The proposed strategy aims for immediate impact on patient safety despite resource constraints.
Conclusions:
- A tailored, resource-aware pharmacovigilance strategy is essential for PICs.
- Initial focus on "problems with medicines" reporting can build momentum for stronger PV systems.
- Collaborative efforts between funding organizations and national health systems are crucial for sustainable PV.
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