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Cerebral meningiomas in children
L Ferrante1, M Acqui, M Artico
1University of Rome La Sapienza, Department of Neurological Sciences, Italy.
Insights
Pediatric cerebral meningiomas are rare brain tumors with distinct characteristics compared to adult cases. This study highlights key differences in presentation and diagnosis in children under 16.
Area of Science:
- Pediatric neuro-oncology
- Neurosurgery
- Neuroradiology
Background:
- Cerebral meningiomas are uncommon central nervous system (CNS) tumors in pediatric populations, accounting for a small percentage of childhood brain tumors and intracranial meningiomas.
- Understanding the unique features of pediatric meningiomas is crucial for accurate diagnosis and effective management.
Purpose of the Study:
- To analyze the characteristics of cerebral meningiomas in patients under 16 years of age.
- To compare pediatric meningiomas with their adult counterparts to identify significant differences.
Main Methods:
- A comprehensive analysis of 197 pediatric cerebral meningioma cases (under 16 years old).
- Data compilation included 178 cases from existing literature and 19 cases from the authors' series.
- Comparative analysis between pediatric and adult meningioma cohorts.
Main Results:
- Pediatric meningiomas show a slight male predominance before age 16.
- Intraventricular location, cystic variants, and lack of dural attachment are more frequent in children.
- Neuroradiological diagnosis of pediatric meningiomas presents greater challenges compared to adults.
Conclusions:
- Pediatric cerebral meningiomas exhibit distinct epidemiological and clinical features compared to adult meningiomas.
- The unique characteristics necessitate tailored diagnostic and therapeutic approaches for children.
- Further research into the specific etiology and optimal management of pediatric meningiomas is warranted.
Abstract:
Cerebral meningiomas are rare tumors in children that represent 1.4% of CNS tumors and 1.5% of intracranial meningiomas. We have analyzed 197 cases of cerebral meningiomas under 16: 178 cases were taken from the available literature and 19 from our series. When comparing pediatric meningiomas with those of adults, we noted some differences. Before the age of 16 there is a slight preference for males; the intraventricular variety is more frequent; cystic meningiomas and the absence of dural attachment are more frequent findings; the neuroradiological diagnosis is more difficult.