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Updated: Mar 18, 2026

Establishing a Mouse Contusion Spinal Cord Injury Model Based on a Minimally Invasive Technique
Published on: September 7, 2022
Spinal Cord Injuries
M Malhotra1, H S Bhatoe2, S M Sudambrekar3
1Clinical Tutor, Department of Surgery, Armed Forces Medical College, Pune-40.
Abstract:
Spinal Cord injury (SCI) is one of the most devastating and demoralizing ailment for both the patient and the medical practitioner. However, with the better understanding of the pathophysiology, better imaging modalities and emphasis on immobilization and rehabilitation has provided a ray of hope to such patients. The initial care aims at immobilization and evacuation by the classical log roll method and focuses on life-saving procedures. Basic imaging should be augmented with an MRI in doubtful cases. Immobilization either external or internal should be followed by early efforts for rehabilitation. The use of steroids during the acute phase has become controversial. The focus of latest studies has shifted to neuroprotective and regenerative agents.
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